Reactome | Tolerance by Mtb to nitric oxide produced by macrophages

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Tolerance by Mtb to nitric oxide produced by macrophages Show undefined attributes

authored	[InstanceEdit:1222281] Stephan, R, 2011-01-10
created	[InstanceEdit:1222482] Jassal, B, 2011-02-28
crossReference	[DatabaseIdentifier:12020769] Mondo:0018076
dbId	1222538
disease	[Disease:1660556] tuberculosis
displayName	Tolerance by Mtb to nitric oxide produced by macrophages
edited	[InstanceEdit:1222482] Jassal, B, 2011-02-28
eventOf	[Pathway:R-HSA-1222499] Latent infection - Other responses of Mtb to phagocytosis - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:9844181] symbiont-mediated detoxification of host-generated reactive oxygen species
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-1500761] Nitrogen dioxide is reduced to NO by F420 - Homo sapiens [Reaction:R-HSA-1222723] Nitric oxide is oxidized to nitrate - Homo sapiens [Reaction:R-HSA-1222431] Peroxynitrite is reduced to nitrite by AhpC - Homo sapiens [Reaction:R-HSA-1500804] Peroxynitrite is reduced by AhpE - Homo sapiens [Reaction:R-HSA-1222755] Peroxynitrite is reduced to nitrite by Tpx - Homo sapiens [Reaction:R-HSA-1222594] Mycothiol scavenges nitrosyl - Homo sapiens [Reaction:R-HSA-1222583] MscR reduces nitrosomycothiol to ammonia - Homo sapiens [Reaction:R-HSA-1222363] MsrA/B reduces peptide-methionine S/R-sulfoxides - Homo sapiens [Reaction:R-HSA-1222712] Nitrosoglutathione gets cleaved to Cys(NO)-Gly - Homo sapiens [Reaction:R-HSA-1500817] Glutathione is taken up by the bacterium - Homo sapiens
isInDisease	true
isInferred	false
lastUpdatedDate	2018-09-30
literatureReference	[LiteratureReference:1222414] Antimicrobial reactive oxygen and nitrogen species: concepts and controversies
maxDepth	2
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Tolerance by Mtb to nitric oxide produced by macrophages
relatedSpecies	[Species:176806] Mycobacterium tuberculosis
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2213261] Warner, D, 2012-04-30
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-1222538
summation	[Summation:1222637] Reactive nitrogen species (RNS), like reactive oxygen specie...
updateTrackers	[UpdateTracker:9778988] Update Tracker - [Pathway:1222538] Tolerance by Mtb to nitric oxide produced by macrophages - v66:[updateContainedRLE] [UpdateTracker:9783888] Update Tracker - [Pathway:1222538] Tolerance by Mtb to nitric oxide produced by macrophages - v55:[addHasEvent]

Referrals

(updatedInstance)	[UpdateTracker:9778988] Update Tracker - [Pathway:1222538] Tolerance by Mtb to nitric oxide produced by macrophages - v66:[updateContainedRLE] [UpdateTracker:9783888] Update Tracker - [Pathway:1222538] Tolerance by Mtb to nitric oxide produced by macrophages - v55:[addHasEvent]
(hasEvent)	[Pathway:R-HSA-1222499] Latent infection - Other responses of Mtb to phagocytosis