Reactome | Mycothiol scavenges nitrosyl

Schema > Reaction > Entries

authored	[InstanceEdit:1222281] Stephan, R, 2011-01-10
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1222482] Jassal, B, 2011-02-28
crossReference	[DatabaseIdentifier:12020769] Mondo:0018076
dbId	1222594
disease	[Disease:1660556] tuberculosis
displayName	Mycothiol scavenges nitrosyl
edited	[InstanceEdit:1222482] Jassal, B, 2011-02-28
eventOf	[Pathway:R-HSA-1222538] Tolerance by Mtb to nitric oxide produced by macrophages - Homo sapiens
followingEvent	[Reaction:R-HSA-1222583] MscR reduces nitrosomycothiol to ammonia - Homo sapiens
input	[SimpleEntity:R-ALL-879289] MSH [cytosol] [SimpleEntity:R-ALL-1222525] NO+ [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:1470071] Innate protection of Mycobacterium smegmatis against the antimicrobial activity of nitric oxide is provided by mycothiol
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Mycothiol scavenges nitrosyl
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-1222631] MSNO [cytosol]
relatedSpecies	[Species:176806] Mycobacterium tuberculosis
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2213261] Warner, D, 2012-04-30
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1222594
summation	[Summation:1222324] Nitrosyl is scavenged by mycothiol (MSH), which is functiona...

(precedingEvent)	[Reaction:R-HSA-1222583] MscR reduces nitrosomycothiol to ammonia
(hasEvent)	[Pathway:R-HSA-1222538] Tolerance by Mtb to nitric oxide produced by macrophages

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