Reactome | Activation and oligomerization of BAK protein

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Activation and oligomerization of BAK protein Show undefined attributes

compartment	[Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:139911] Hardwick, JM, Tsujimoto, Y, 2004-08-09 19:10:09
crossReference	[DatabaseIdentifier:12819457] BioModels Database:BIOMD0000000220
dbId	111452
displayName	Activation and oligomerization of BAK protein
eventOf	[Pathway:R-HSA-109606] Intrinsic Pathway for Apoptosis - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:2455174] positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-168848] tBID binds to inactive BAK protein - Homo sapiens [Reaction:R-HSA-139895] tBID activates BAK protein - Homo sapiens [Reaction:R-HSA-114263] Oligomerization of BAK at the mitochondrial membrane - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2013-03-31
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	Activation and oligomerization of BAK protein
orthologousEvent	[Pathway:R-GGA-111452] Activation and oligomerization of BAK protein - Gallus gallus [Pathway:R-SSC-111452] Activation and oligomerization of BAK protein - Sus scrofa [Pathway:R-BTA-111452] Activation and oligomerization of BAK protein - Bos taurus [Pathway:R-CFA-111452] Activation and oligomerization of BAK protein - Canis familiaris [Pathway:R-RNO-111452] Activation and oligomerization of BAK protein - Rattus norvegicus [Pathway:R-MMU-111452] Activation and oligomerization of BAK protein - Mus musculus
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-111452
summation	[Summation:213108] tBID binds to its mitochondrial partner BAK to release cytoc...
updateTrackers	[UpdateTracker:9791927] Update Tracker - [Pathway:111452] Activation and oligomerization of BAK protein - v24:[addSummation] [UpdateTracker:9787668] Update Tracker - [Pathway:111452] Activation and oligomerization of BAK protein - v44:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9791927] Update Tracker - [Pathway:111452] Activation and oligomerization of BAK protein - v24:[addSummation] [UpdateTracker:9787668] Update Tracker - [Pathway:111452] Activation and oligomerization of BAK protein - v44:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-109606] Intrinsic Pathway for Apoptosis