Activation and oligomerization of BAK protein

Stable Identifier
R-HSA-111452
Type
Pathway
Species
Homo sapiens
Compartment
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General
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tBID binds to its mitochondrial partner BAK to release cytochrome c. Activated tBID results in an allosteric activation of BAK. This may induce its intramembranous oligomerization into a pore for cytochrome c efflux.

Participants
Participant Of
Event Information
Orthologous Events
Cross References
BioModels Database
Created