Reactome | LIG3:XRCC1 [nucleoplasm]

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LIG3:XRCC1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-110343] LIG3:XRCC1:POLB:dsDNA [nucleoplasm] - Homo sapiens [Complex:R-HSA-5649729] NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB(3'Pi)-gap-dsDNA [nucleoplasm] - Homo sapiens [Complex:R-HSA-110341] LIG3:XRCC1:POLB:SSB-dsDNA [nucleoplasm] - Homo sapiens [Complex:R-HSA-5649722] NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:dsDNA [nucleoplasm] - Homo sapiens [Complex:R-HSA-5649733] NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-110376] Recruitment of LIG3:XRCC1 complex to the site of repair by POLB - Homo sapiens [Reaction:R-HSA-5649726] LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA - Homo sapiens [Reaction:R-HSA-5687673] MRN recruits LIG3:XRCC1 to MMEJ sites - Homo sapiens
created	[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00
dbId	110338
displayName	LIG3:XRCC1 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-53789] LIG3 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-67455] XRCC1 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-110338] LIG3:XRCC1 [nucleoplasm] - Mus musculus [Complex:R-RNO-110338] LIG3:XRCC1 [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-110338] LIG3:XRCC1 [nucleoplasm] - Canis familiaris [Complex:R-BTA-110338] LIG3:XRCC1 [nucleoplasm] - Bos taurus [Complex:R-SSC-110338] LIG3:XRCC1 [nucleoplasm] - Sus scrofa [Complex:R-DRE-110338] LIG3:XRCC1 [nucleoplasm] - Danio rerio [Complex:R-XTR-110338] LIG3:XRCC1 [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-110338] LIG3:XRCC1 [nucleoplasm] - Gallus gallus [Complex:R-DME-110338] LIG3:XRCC1 [nucleoplasm] - Drosophila melanogaster [Complex:R-DDI-110338] LIG3:XRCC1 [nucleoplasm] - Dictyostelium discoideum
literatureReference	[LiteratureReference:111257] Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.
maxDepth	2
memberOf	[DefinedSet:R-HSA-5690475] LIG1,LIG3:XRCC1 [nucleoplasm] - Homo sapiens
modified	[InstanceEdit:5649639] Orlic-Milacic, Marija, 2014-11-20
name	LIG3:XRCC1
producedByEvent	[Reaction:R-HSA-110380] Dissociation of LIG3:XRCC1 complex from the BER site - Homo sapiens [Reaction:R-HSA-5687675] LIG3 ligates remaining SSBs in MMEJ - Homo sapiens [Reaction:R-HSA-5649724] LIG3:XRCC1, POLB, NEIL1,NEIL2 and PNKP dissociate from the BER site - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-110338
updateTrackers	[UpdateTracker:9889831] Update Tracker - [Complex:110338] LIG3:XRCC1 [nucleoplasm] - v52:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9889831] Update Tracker - [Complex:110338] LIG3:XRCC1 [nucleoplasm] - v52:[modifyName]
(output)	[Reaction:R-HSA-110380] Dissociation of LIG3:XRCC1 complex from the BER site [Reaction:R-HSA-5649724] LIG3:XRCC1, POLB, NEIL1,NEIL2 and PNKP dissociate from the BER site [Reaction:R-HSA-5687675] LIG3 ligates remaining SSBs in MMEJ
(hasComponent)	[Complex:R-HSA-110343] LIG3:XRCC1:POLB:dsDNA [nucleoplasm] [Complex:R-HSA-110341] LIG3:XRCC1:POLB:SSB-dsDNA [nucleoplasm] [Complex:R-HSA-110339] LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] [Complex:R-HSA-5649729] NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB(3'Pi)-gap-dsDNA [nucleoplasm] [Complex:R-HSA-5649816] NEIL1,NEIL2:POLB:LIG3:XRCC1:PNKP:SSB-gap-dsDNA [nucleoplasm] [Complex:R-HSA-5649722] NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:dsDNA [nucleoplasm] [Complex:R-HSA-5649733] NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm] [Complex:R-HSA-5687677] Extended microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:LIG3:XRCC1 [nucleoplasm]
(input)	[Reaction:R-HSA-110376] Recruitment of LIG3:XRCC1 complex to the site of repair by POLB [Reaction:R-HSA-5649726] LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA [Reaction:R-HSA-5687673] MRN recruits LIG3:XRCC1 to MMEJ sites
(hasMember)	[DefinedSet:R-HSA-5690475] LIG1,LIG3:XRCC1 [nucleoplasm]

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