Reactome | FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP

Schema > Reaction > Entries

FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP Show undefined attributes

authored	[InstanceEdit:1028796] Dall'Olio, GM, 2010-11-18
catalystActivity	[CatalystActivity:1028794] glycoprotein 6-alpha-L-fucosyltransferase activity of FUT8 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:1028792] Jassal, B, 2010-11-18
dbId	1028788
displayName	FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP
edited	[InstanceEdit:1028792] Jassal, B, 2010-11-18
eventOf	[Pathway:R-HSA-975578] Reactions specific to the complex N-glycan synthesis pathway - Homo sapiens
followingEvent	[Reaction:R-HSA-5693807] FUCA1 hydrolyses NGP:1,6-GlcNAc - Homo sapiens
input	[SimpleEntity:R-ALL-205683] GDP-Fuc [Golgi lumen] [SimpleEntity:R-ALL-975910] NGP [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1028783] Expression of human alpha-l-fucosyltransferase gene homologs in monkey kidney COS cells and modification of potential fucosyltransferase acceptor substrates by an endogenous glycosidase [LiteratureReference:1028791] Mapping of the alpha-1,6-fucosyltransferase gene, FUT8, to human chromosome 14q24.3 [LiteratureReference:1028781] Genomic structure and promoter analysis of the human alpha1, 6-fucosyltransferase gene (FUT8)
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP Addition of alpha 1,6 fucose to the first GlcNAc of the N-glycan
orthologousEvent	[Reaction:R-BTA-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Bos taurus [Reaction:R-DDI-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Dictyostelium discoideum [Reaction:R-CEL-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Caenorhabditis elegans [Reaction:R-DME-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Drosophila melanogaster [Reaction:R-GGA-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Gallus gallus [Reaction:R-XTR-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Xenopus tropicalis [Reaction:R-DRE-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Danio rerio [Reaction:R-SSC-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Sus scrofa [Reaction:R-CFA-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Canis familiaris [Reaction:R-RNO-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Rattus norvegicus [Reaction:R-MMU-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Mus musculus
output	[SimpleEntity:R-ALL-205689] GDP [Golgi lumen] [OtherEntity:R-ALL-1028779] NGP:1,6-GlcNAc [Golgi lumen]
precedingEvent	[Reaction:R-HSA-742345] SLC35C1 transports GDP-Fuc from cytosol to Golgi lumen - Homo sapiens
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1028788
summation	[Summation:1028793] Addition of a fucose moiety as an alpha 1-6 linkage to the f...
updateTrackers	[UpdateTracker:9784175] Update Tracker - [Reaction:1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - v54:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9784175] Update Tracker - [Reaction:1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - v54:[modifyText]
(hasEvent)	[Pathway:R-HSA-975578] Reactions specific to the complex N-glycan synthesis pathway
(precedingEvent)	[Reaction:R-HSA-5693807] FUCA1 hydrolyses NGP:1,6-GlcNAc