FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP

Stable Identifier
Reaction [transition]
Homo sapiens
Addition of alpha 1,6 fucose to the first GlcNAc of the N-glycan
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Addition of a fucose moiety as an alpha 1-6 linkage to the first GlcNAc residue of the N-glycan (Clarke JL, Watkins WM 1999; Yamaguchi Y et al, 1999; Yamaguchi Y et al 2000).

Literature References
PubMed ID Title Journal Year
10343104 Mapping of the alpha-1,6-fucosyltransferase gene, FUT8, to human chromosome 14q24.3

Fujii, J, Miyoshi, O, Uozumi, N, Yamaguchi, Y, Ikeda, Y, Inoue, S, Yanagidani, S, Niikawa, N, Taniguchi, N, Egashira, M

Cytogenet Cell Genet 1999
10814706 Genomic structure and promoter analysis of the human alpha1, 6-fucosyltransferase gene (FUT8)

Fujii, J, Uozumi, N, Ihara, H, Inoue, S, Ikeda, Y, Yanagidani, S, Takahashi, T, Taniguchi, N, Yamaguchi, Y, Sasho, C, Tanaka, T

Glycobiology 2000
9949196 Expression of human alpha-l-fucosyltransferase gene homologs in monkey kidney COS cells and modification of potential fucosyltransferase acceptor substrates by an endogenous glycosidase

Watkins, WM, Clarke, JL

Glycobiology 1999
Catalyst Activity

glycoprotein 6-alpha-L-fucosyltransferase activity of FUT8 [Golgi membrane]

Orthologous Events
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