Reactome | FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP

Schema > Reaction > Entries

FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP Show undefined attributes

catalystActivity	[CatalystActivity:10150925] glycoprotein 6-alpha-L-fucosyltransferase activity of FUT8 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10150927
displayName	FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP
eventOf	[Pathway:R-RNO-975578] Reactions specific to the complex N-glycan synthesis pathway - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-5693807] FUCA1 hydrolyses NGP:1,6-GlcNAc - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Homo sapiens
input	[SimpleEntity:R-ALL-205683] GDP-Fuc [Golgi lumen] [SimpleEntity:R-ALL-975910] NGP [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP Addition of alpha 1,6 fucose to the first GlcNAc of the N-glycan
output	[SimpleEntity:R-ALL-205689] GDP [Golgi lumen] [OtherEntity:R-ALL-1028779] NGP:1,6-GlcNAc [Golgi lumen]
precedingEvent	[Reaction:R-RNO-742345] SLC35C1 transports GDP-Fuc from cytosol to Golgi lumen - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1028788
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-975578] Reactions specific to the complex N-glycan synthesis pathway
(precedingEvent)	[Reaction:R-RNO-5693807] FUCA1 hydrolyses NGP:1,6-GlcNAc
(inferredTo)	[Reaction:R-HSA-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP

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