Reactome | PRKCZ recruits RAS in response to estrogen stimulation

Schema > Reaction > Entries

PRKCZ recruits RAS in response to estrogen stimulation Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10816595
displayName	PRKCZ recruits RAS in response to estrogen stimulation
eventOf	[Pathway:R-GGA-9634635] Estrogen-stimulated signaling through PRKCZ - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-GGA-9632910] ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus - Gallus gallus [BlackBoxEvent:R-GGA-9632918] PRKCZ stimulates RAS nucleotide exchange in response to estrogen - Gallus gallus
inferredFrom	[Reaction:R-HSA-9632906] PRKCZ recruits RAS in response to estrogen stimulation - Homo sapiens
input	[Complex:R-GGA-109796] p21 RAS:GDP [plasma membrane] [Complex:R-GGA-9632853] PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PRKCZ recruits RAS in response to estrogen stimulation
output	[Complex:R-GGA-9632908] PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane]
precedingEvent	[Reaction:R-GGA-9632858] PRKCZ autophosphorylates downstream of estrogen stimulation - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9632906
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9634635] Estrogen-stimulated signaling through PRKCZ
(precedingEvent)	[BlackBoxEvent:R-GGA-9632910] ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus [BlackBoxEvent:R-GGA-9632918] PRKCZ stimulates RAS nucleotide exchange in response to estrogen
(inferredTo)	[Reaction:R-HSA-9632906] PRKCZ recruits RAS in response to estrogen stimulation

Cite Us!