Reactome | p-T68-CHEK2 dimerizes

Schema > Reaction > Entries

p-T68-CHEK2 dimerizes Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10794471
displayName	p-T68-CHEK2 dimerizes
eventOf	[Pathway:R-GGA-69473] G2/M DNA damage checkpoint - Gallus gallus [Pathway:R-GGA-5693565] Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-5683792] p-T68-CHEK2 autophosphorylates - Gallus gallus
inferredFrom	[Reaction:R-HSA-5683774] p-T68-CHEK2 dimerizes - Homo sapiens
input	2 × [EntityWithAccessionedSequence:R-GGA-113825] phospho-CHEK2 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	p-T68-CHEK2 dimerizes
output	[Complex:R-GGA-5683773] p-T68-CHEK2 dimer [nucleoplasm]
precedingEvent	[Reaction:R-GGA-69891] Phosphorylation and activation of CHEK2 by ATM - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-5683774
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-5693565] Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks [Pathway:R-GGA-69473] G2/M DNA damage checkpoint
(precedingEvent)	[Reaction:R-GGA-5683792] p-T68-CHEK2 autophosphorylates
(inferredTo)	[Reaction:R-HSA-5683774] p-T68-CHEK2 dimerizes