Reactome | Association of LBP with bacterial LPS

Schema > Reaction > Entries

authored	[InstanceEdit:749468] Shamovsky, V, 2010-05-18
category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:434122] Shamovsky, V, 2009-08-26
dbId	433940
displayName	Association of LBP with bacterial LPS
edited	[InstanceEdit:994006] Shamovsky, V, 2010-11-05
eventOf	[Pathway:R-GGA-433794] TLR4 cascade - Gallus gallus
followingEvent	[Reaction:R-GGA-434003] LPS binding to CD14 co-receptor - Gallus gallus
input	[GenomeEncodedEntity:R-GGA-433876] Lipopolysaccharide binding protein [extracellular region] [SimpleEntity:R-ALL-166005] LPS [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:433799] Lipopolysaccharide binding protein/CD14/ TLR4-dependent recognition of salmonella LPS induces the functional activation of chicken heterophils and up-regulation of pro-inflammatory cytokine and chemokine gene expression in these cells [LiteratureReference:165814] Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Association of LBP with bacterial LPS
output	[Complex:R-GGA-433795] LBP : LPS complex [extracellular region]
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:977269] D'Eustachio, P, 2010-10-15
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-433940
summation	[Summation:975752] The role of chicken lipopolysaccharide-binding protein (LBP)...

(precedingEvent)	[Reaction:R-GGA-434003] LPS binding to CD14 co-receptor
(hasEvent)	[Pathway:R-GGA-433794] TLR4 cascade

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