Reactome | Non-homologous end joining (NHEJ)

Schema > Pathway > Entries

Non-homologous end joining (NHEJ) Show undefined attributes

authored	[InstanceEdit:399969] Saxena, A, 2008-07-07 18:55:16
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:353491] Saxena, A, 2008-06-12 16:39:18
dbId	353423
displayName	Non-homologous end joining (NHEJ)
edited	[InstanceEdit:418967] D'Eustachio, P, 2009-04-27 17:09:41
eventOf	[Pathway:R-GGA-353371] Double strand break repair - Gallus gallus
goBiologicalProcess	[GO_BiologicalProcess:17665] double-strand break repair via nonhomologous end joining
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-353226] Association of Ku heterodimer with ends of DNA double-strand breaks - Gallus gallus [Reaction:R-GGA-353455] Autophosphorylation of DNA-PKcs - Gallus gallus [Reaction:R-GGA-353283] Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - Gallus gallus [Reaction:R-GGA-353265] Interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB - Gallus gallus [Reaction:R-GGA-353313] Removal of 3'-phosphoglycolate (PG) moiety from DSB ends - Gallus gallus [Reaction:R-GGA-353475] Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex - Gallus gallus [Reaction:R-GGA-353298] Removal of repair proteins and ligation of the processed ends of the DNA double-strand break - Gallus gallus
isInDisease	false
isInferred	false
lastUpdatedDate	2017-06-22
literatureReference	[LiteratureReference:353428] Differential usage of non-homologous end-joining and homologous recombination in double strand break repair
maxDepth	2
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Non-homologous end joining (NHEJ)
releaseDate	2009-06-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:418616] Borowiec, JA, 2009-04-23 20:19:22
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-353423
summation	[Summation:391633] The NHEJ pathway is initiated in response to the formation o...
updateTrackers	[UpdateTracker:9781359] Update Tracker - [Pathway:353423] Non-homologous end joining (NHEJ) - v61:[updateContainedRLE] [UpdateTracker:9784295] Update Tracker - [Pathway:353423] Non-homologous end joining (NHEJ) - v54:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9781359] Update Tracker - [Pathway:353423] Non-homologous end joining (NHEJ) - v61:[updateContainedRLE] [UpdateTracker:9784295] Update Tracker - [Pathway:353423] Non-homologous end joining (NHEJ) - v54:[updateContainedRLE]
(hasEvent)	[Pathway:R-GGA-353371] Double strand break repair