Reactome | Association of Ku heterodimer with ends of DNA double-strand breaks

Schema > Reaction > Entries

authored	[InstanceEdit:399969] Saxena, A, 2008-07-07 18:55:16
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:353491] Saxena, A, 2008-06-12 16:39:18
dbId	353226
displayName	Association of Ku heterodimer with ends of DNA double-strand breaks
edited	[InstanceEdit:418967] D'Eustachio, P, 2009-04-27 17:09:41
eventOf	[Pathway:R-GGA-353423] Non-homologous end joining (NHEJ) - Gallus gallus
followingEvent	[Reaction:R-GGA-353455] Autophosphorylation of DNA-PKcs - Gallus gallus [Reaction:R-GGA-353283] Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - Gallus gallus
input	[OtherEntity:R-ALL-75165] DNA double-strand break ends [nucleoplasm] [Complex:R-GGA-353530] Ku-heterodimer complex [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:353219] Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Association of Ku heterodimer with ends of DNA double-strand breaks
output	[Complex:R-GGA-353518] Ku:DNA DSB ends [nucleoplasm]
releaseDate	2009-06-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:418616] Borowiec, JA, 2009-04-23 20:19:22
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-353226
summation	[Summation:353480] A DNA double strand break results when two single strand bre...

(hasEvent)	[Pathway:R-GGA-353423] Non-homologous end joining (NHEJ)
(precedingEvent)	[Reaction:R-GGA-353283] Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks [Reaction:R-GGA-353455] Autophosphorylation of DNA-PKcs

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