Reactome | Interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB

Schema > Reaction > Entries

authored	[InstanceEdit:399969] Saxena, A, 2008-07-07 18:55:16
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:353491] Saxena, A, 2008-06-12 16:39:18
dbId	353265
displayName	Interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB
edited	[InstanceEdit:418967] D'Eustachio, P, 2009-04-27 17:09:41
eventOf	[Pathway:R-GGA-353423] Non-homologous end joining (NHEJ) - Gallus gallus
followingEvent	[Reaction:R-GGA-353313] Removal of 3'-phosphoglycolate (PG) moiety from DSB ends - Gallus gallus
inferredFrom	[Reaction:R-HSA-5693615] Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis - Homo sapiens
input	2 × [Complex:R-GGA-353384] DNA-PK-Ku-DNA complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB
output	[Complex:R-GGA-353424] DNA-PK synaptic complex [nucleoplasm]
precedingEvent	[Reaction:R-GGA-353283] Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - Gallus gallus
releaseDate	2009-06-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:418616] Borowiec, JA, 2009-04-23 20:19:22
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-353265
summation	[Summation:353231] The DNA-PK-Ku complex translocates away from the DSB. Subseq...

(precedingEvent)	[Reaction:R-GGA-353313] Removal of 3'-phosphoglycolate (PG) moiety from DSB ends
(hasEvent)	[Pathway:R-GGA-353423] Non-homologous end joining (NHEJ)
(inferredTo)	[Reaction:R-HSA-5693615] Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis

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