Reactome | Metallothioneins bind metals

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Metallothioneins bind metals Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650056
displayName	Metallothioneins bind metals
eventOf	[Pathway:R-DRE-5660526] Response to metal ions - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:78245] response to metal ion
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DRE-5661217] MT1A binds zinc - Danio rerio [Reaction:R-DRE-5661230] MT1A binds arsenic - Danio rerio [Reaction:R-DRE-5662608] MT2A binds cadmium - Danio rerio [Reaction:R-DRE-5662986] MT2A binds copper - Danio rerio [Reaction:R-DRE-5662606] MT3 binds zinc - Danio rerio [Reaction:R-DRE-5662620] MT3 binds cadmium - Danio rerio [BlackBoxEvent:R-DRE-5662613] MT3 exchanges zinc for copper - Danio rerio
inferredFrom	[Pathway:R-HSA-5661231] Metallothioneins bind metals - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Metallothioneins bind metals
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-5661231
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-5660526] Response to metal ions
(inferredTo)	[Pathway:R-HSA-5661231] Metallothioneins bind metals

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