Reactome | Response to metal ions

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650058
displayName	Response to metal ions
eventOf	[TopLevelPathway:R-DRE-8953897] Cellular responses to stimuli - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:78245] response to metal ion
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DRE-5661231] Metallothioneins bind metals - Danio rerio
inferredFrom	[Pathway:R-HSA-5660526] Response to metal ions - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Response to metal ions
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-5660526
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[TopLevelPathway:R-DRE-8953897] Cellular responses to stimuli
(inferredTo)	[Pathway:R-HSA-5660526] Response to metal ions

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