Reactome | MT2A binds copper

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10615473
displayName	MT2A binds copper
eventOf	[Pathway:R-DRE-5661231] Metallothioneins bind metals - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5662986] MT2A binds copper - Homo sapiens
input	10 × [SimpleEntity:R-ALL-3299744] Cu1+ [cytosol] [EntityWithAccessionedSequence:R-DRE-5660412] MT1A [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MT2A binds copper
output	[Complex:R-DRE-5662969] MT2A:10Cu1+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5662986
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-5661231] Metallothioneins bind metals
(inferredTo)	[Reaction:R-HSA-5662986] MT2A binds copper

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