Reactome | MT1A binds arsenic

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10615407
displayName	MT1A binds arsenic
eventOf	[Pathway:R-DRE-5661231] Metallothioneins bind metals - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5661230] MT1A binds arsenic - Homo sapiens
input	6 × [SimpleEntity:R-ALL-5661216] As3+ [cytosol] [EntityWithAccessionedSequence:R-DRE-5660412] MT1A [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MT1A binds arsenic
output	[Complex:R-DRE-5661211] MT1A:6As3+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5661230
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-5661231] Metallothioneins bind metals
(inferredTo)	[Reaction:R-HSA-5661230] MT1A binds arsenic

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