Reactome | vcla [cytosol]

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DRE-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] - Danio rerio [Complex:R-DRE-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] - Danio rerio [Complex:R-DRE-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] - Danio rerio [Complex:R-DRE-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] - Danio rerio [Complex:R-DRE-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] - Danio rerio [Complex:R-DRE-9934508] Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] - Danio rerio
consumedByEvent	[Reaction:R-DRE-9861485] Calpain2 (m-Calpain, CAPN2:CAPNS:Ca2+) cleaves VCL (Vinculin) - Danio rerio [Reaction:R-DRE-9934294] CDH1-associated CTNNA1 binds VCL - Danio rerio [Reaction:R-DRE-9934294] CDH1-associated CTNNA1 binds VCL - Danio rerio [Reaction:R-DRE-9934294] CDH1-associated CTNNA1 binds VCL - Danio rerio [Reaction:R-DRE-9934294] CDH1-associated CTNNA1 binds VCL - Danio rerio [Reaction:R-DRE-9934294] CDH1-associated CTNNA1 binds VCL - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10588192
displayName	vcla [cytosol]
endCoordinate	1134
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-350753] VCL [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-DRE-482771] Platelet releasate cytosolic proteins [cytosol] - Danio rerio
name	vcla VCL B3DI32
referenceEntity	[ReferenceGeneProduct:uniprot:B3DI32] UniProt:B3DI32
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68323] Danio rerio
stId	R-DRE-350753
startCoordinate	1

(hasMember)	[DefinedSet:R-DRE-482771] Platelet releasate cytosolic proteins [cytosol]
(input)	[Reaction:R-DRE-9861485] Calpain2 (m-Calpain, CAPN2:CAPNS:Ca2+) cleaves VCL (Vinculin) [Reaction:R-DRE-9934294] CDH1-associated CTNNA1 binds VCL
(hasComponent)	[Complex:R-DRE-9934508] Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] [Complex:R-DRE-9934440] trans-homotypic CDH1 cluster:F-actin:VCL [plasma membrane] [Complex:R-DRE-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] [Complex:R-DRE-354132] Vinculin bound to PIP2 [plasma membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-350753] VCL [cytosol]

vcla [cytosol] Show undefined attributes

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