Reactome | VCL [cytosol]

Schema > EntityWithAccessionedSequence > Entries

VCL [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] - Homo sapiens [Complex:R-HSA-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] - Homo sapiens [Complex:R-HSA-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] - Homo sapiens [Complex:R-HSA-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] - Homo sapiens [Complex:R-HSA-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] - Homo sapiens [Complex:R-HSA-9934506] trans-Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] - Homo sapiens [Complex:R-HSA-445775] integrin:cytoskeletal adhesion complex [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9861485] Calpain2 (m-Calpain, CAPN2:CAPNS:Ca2+) cleaves VCL (Vinculin) - Homo sapiens [Reaction:R-HSA-9934294] CDH1-associated CTNNA1 binds VCL - Homo sapiens [Reaction:R-HSA-9934294] CDH1-associated CTNNA1 binds VCL - Homo sapiens [Reaction:R-HSA-9934294] CDH1-associated CTNNA1 binds VCL - Homo sapiens [Reaction:R-HSA-9934294] CDH1-associated CTNNA1 binds VCL - Homo sapiens [Reaction:R-HSA-9934294] CDH1-associated CTNNA1 binds VCL - Homo sapiens
created	[InstanceEdit:350733] Garapati, P V, 2008-05-20 15:04:20
dbId	350753
displayName	VCL [cytosol]
endCoordinate	1134
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-350753] Vcl [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-350753] Vcl [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-350753] VCL [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-350753] VCL [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-350753] VCL [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-350753] vcla [cytosol] - Danio rerio [GenomeEncodedEntity:R-XTR-350753] Ghost homologue of VCL [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-350753] VCL [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-350753] Vinc [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-350753] deb-1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-350753] fip-2 [cytosol] - Dictyostelium discoideum
maxDepth	1
memberOf	[DefinedSet:R-HSA-482771] Platelet releasate cytosolic proteins [cytosol] - Homo sapiens
modified	[InstanceEdit:9938525] D'Eustachio, Peter, 2025-02-17
name	VCL Vinculin
referenceEntity	[ReferenceGeneProduct:uniprot:P18206] UniProt:P18206 VCL
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-350753
startCoordinate	1
updateTrackers	[UpdateTracker:9939872] Update Tracker - [EntityWithAccessionedSequence:350753] VCL [cytosol] - v92:[modifyStartCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9939872] Update Tracker - [EntityWithAccessionedSequence:350753] VCL [cytosol] - v92:[modifyStartCoordinate]
(hasComponent)	[Complex:R-HSA-445775] integrin:cytoskeletal adhesion complex [plasma membrane] [Complex:R-HSA-9934506] trans-Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] [Complex:R-HSA-9934508] Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] [Complex:R-HSA-9934440] trans-homotypic CDH1 cluster:F-actin:VCL [plasma membrane] [Complex:R-HSA-9934501] Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] [Complex:R-HSA-354132] Vinculin bound to PIP2 [plasma membrane]
(hasMember)	[DefinedSet:R-HSA-482771] Platelet releasate cytosolic proteins [cytosol]
(input)	[Reaction:R-HSA-9861485] Calpain2 (m-Calpain, CAPN2:CAPNS:Ca2+) cleaves VCL (Vinculin) [Reaction:R-HSA-9934294] CDH1-associated CTNNA1 binds VCL

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