Reactome | HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex

Schema > Reaction > Entries

HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex Show undefined attributes

catalystActivity	[CatalystActivity:10897997] ATP hydrolysis activity of ESR:ESTG:chaperone complex [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10897999
displayName	HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex
eventOf	[Pathway:R-DME-8939211] ESR-mediated signaling - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-8939201] ESR dimerizes - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-8939203] HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex - Homo sapiens
input	[DefinedSet:R-DME-9709543] ESR:ESTG:chaperone complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-DME-5082403] cPges [nucleoplasm] [DefinedSet:R-DME-9709550] ESR:ESTG [nucleoplasm] 2 × [DefinedSet:R-DME-5082416] HSP-90 [nucleoplasm] 2 × [SimpleEntity:R-ALL-113550] Pi [nucleoplasm] 2 × [CandidateSet:R-DME-8939175] TPR-containing co-chaperones [nucleoplasm]
precedingEvent	[Reaction:R-DME-8939204] ESTG binds ESR1:chaperone complex - Drosophila melanogaster [Reaction:R-DME-9709547] ESTG binds ESR2:chaperone complex - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8939203
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-8939211] ESR-mediated signaling
(precedingEvent)	[Reaction:R-DME-8939201] ESR dimerizes
(inferredTo)	[Reaction:R-HSA-8939203] HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex

Cite Us!