Reactome | TPR-containing co-chaperones [nucleoplasm]

Schema > CandidateSet > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DME-8939185] ESR1:chaperone complex [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-8939185] ESR1:chaperone complex [nucleoplasm] - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10897986
displayName	TPR-containing co-chaperones [nucleoplasm]
hasCandidate	[EntityWithAccessionedSequence:R-DME-8939162] Fkbp59 [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-5683410] PpD3 [nucleoplasm] - Drosophila melanogaster
hasMember	[EntityWithAccessionedSequence:R-DME-8939168] Dmel\CG15767 [nucleoplasm] - Drosophila melanogaster
inDisease	false
inferredFrom	[CandidateSet:R-HSA-8939175] TPR-containing co-chaperones [nucleoplasm] - Homo sapiens
maxDepth	2
name	TPR-containing co-chaperones
producedByEvent	[Reaction:R-DME-8939203] HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex - Drosophila melanogaster [Reaction:R-DME-8939203] HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex - Drosophila melanogaster [BlackBoxEvent:R-DME-9032751] Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3 - Drosophila melanogaster
schemaClass	CandidateSet
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8939175

(output)	[BlackBoxEvent:R-DME-9032751] Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3 [Reaction:R-DME-8939203] HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex
(hasComponent)	[Complex:R-DME-8939185] ESR1:chaperone complex [nucleoplasm] [Complex:R-DME-9709546] ESR2:chaperone complex [nucleoplasm]
(inferredTo)	[CandidateSet:R-HSA-8939175] TPR-containing co-chaperones [nucleoplasm]