Reactome | Fc epsilon receptor (FCERI) signaling

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Fc epsilon receptor (FCERI) signaling Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10911294
displayName	Fc epsilon receptor (FCERI) signaling
eventOf	[Pathway:R-DME-168249] Innate Immune System - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2132801] Fc-epsilon receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DME-2871796] FCERI mediated MAPK activation - Drosophila melanogaster [Pathway:R-DME-2871809] FCERI mediated Ca+2 mobilization - Drosophila melanogaster [Pathway:R-DME-2871837] FCERI mediated NF-kB activation - Drosophila melanogaster [Pathway:R-DME-2730905] Role of LAT2/NTAL/LAB on calcium mobilization - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-2454202] Fc epsilon receptor (FCERI) signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Fc epsilon receptor (FCERI) signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-2454202
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEncapsulatedEvent)	[Pathway:R-DME-5673001] RAF/MAP kinase cascade
(hasEvent)	[Pathway:R-DME-168249] Innate Immune System
(inferredTo)	[Pathway:R-HSA-2454202] Fc epsilon receptor (FCERI) signaling

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