Reactome | FCERI mediated Ca+2 mobilization

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FCERI mediated Ca+2 mobilization Show undefined attributes

compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane [Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10912580
displayName	FCERI mediated Ca+2 mobilization
eventOf	[Pathway:R-DME-2454202] Fc epsilon receptor (FCERI) signaling - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-2730858] Autophosphorylation of BTK/ITK - Drosophila melanogaster [Reaction:R-DME-2730847] Hydrolysis of PIP2 by PLCG - Drosophila melanogaster [Reaction:R-DME-2730872] Activation of Calcineurin - Drosophila melanogaster [BlackBoxEvent:R-DME-2730849] Calcineurin binds and dephosphorylates NFAT - Drosophila melanogaster [Reaction:R-DME-2730867] Translocation of CaN:CaM:NFAT to nucleus - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-2871809] FCERI mediated Ca+2 mobilization - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	FCERI mediated Ca+2 mobilization
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-2871809
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-2454202] Fc epsilon receptor (FCERI) signaling
(inferredTo)	[Pathway:R-HSA-2871809] FCERI mediated Ca+2 mobilization

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