Reactome | Formation of the activated receptor complex

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Formation of the activated receptor complex Show undefined attributes

authored	[InstanceEdit:386954] Williams, MG, 2006-11-02 16:49:12
created	[InstanceEdit:205673] Williams, MG, 2006-11-03 15:40:44
dbId	209209
displayName	Formation of the activated receptor complex
edited	[InstanceEdit:205673] Williams, MG, 2006-11-03 15:40:44
eventOf	[Pathway:R-DME-209405] JAK/STAT pathway - Drosophila melanogaster
followingEvent	[Pathway:R-DME-209228] Formation of the activated STAT92E dimer and transport to the nucleus - Drosophila melanogaster
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-209245] Tyrosine kinase Hopscotch (HOP) binds to the transmembrane cytokine receptor Domeless (DOME) to form the HOP:DOME complex - Drosophila melanogaster [Reaction:R-DME-209231] DOME:HOP complex forms a dimer at the plasma membrane - Drosophila melanogaster [Reaction:R-DME-209255] UPD ligand binds to the HOP:DOME:DOME:HOP complex and activates HOP - Drosophila melanogaster [Reaction:R-DME-209336] Activated HOP is autophosphorylated and/or transphosphorylated - Drosophila melanogaster [Reaction:R-DME-209160] Phosphorylated HOP phosphorylates DOME - Drosophila melanogaster
isInDisease	false
isInferred	false
lastUpdatedDate	2020-03-16
literatureReference	[LiteratureReference:208119] JAK/STAT signalling in Drosophila: insights into conserved regulatory and cellular functions
maxDepth	2
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Formation of the activated receptor complex
releaseDate	2009-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:386947] Perrimon, N, 2008-01-16 11:04:04
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-209209
summation	[Summation:9038601] Spatzle (SPZ) dimer binding leads to Toll (TL) receptor homo...
updateTrackers	[UpdateTracker:9777290] Update Tracker - [Pathway:209209] Formation of the activated receptor complex - v72:[modifyText] [UpdateTracker:9779470] Update Tracker - [Pathway:209209] Formation of the activated receptor complex - v65:[addSummation]

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(updatedInstance)	[UpdateTracker:9777290] Update Tracker - [Pathway:209209] Formation of the activated receptor complex - v72:[modifyText] [UpdateTracker:9779470] Update Tracker - [Pathway:209209] Formation of the activated receptor complex - v65:[addSummation]
(precedingEvent)	[Pathway:R-DME-209228] Formation of the activated STAT92E dimer and transport to the nucleus
(hasEvent)	[Pathway:R-DME-209405] JAK/STAT pathway