Reactome | Phosphorylated HOP phosphorylates DOME

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Phosphorylated HOP phosphorylates DOME Show undefined attributes

authored	[InstanceEdit:386954] Williams, MG, 2006-11-02 16:49:12
catalystActivity	[CatalystActivity:5263602] protein tyrosine kinase activity of Phospho HOP:DOME:UPD:DOME:Phospho HOP [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:205673] Williams, MG, 2006-11-03 15:40:44
dbId	209160
displayName	Phosphorylated HOP phosphorylates DOME
edited	[InstanceEdit:205673] Williams, MG, 2006-11-03 15:40:44
eventOf	[Pathway:R-DME-209209] Formation of the activated receptor complex - Drosophila melanogaster
figure	[Figure:208685] /figures/ADrosJAKSTAT05.jpg
followingEvent	[Reaction:R-DME-209361] STAT92E binds to phosphorylated HOP and phosphorylated DOME - Drosophila melanogaster
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-DME-206905] Phospho HOP:DOME:UPD:DOME:Phospho HOP [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:208179] mom identifies a receptor for the Drosophila JAK/STAT signal transduction pathway and encodes a protein distantly related to the mammalian cytokine receptor family [LiteratureReference:208116] Signaling mechanisms through gp130: a model of the cytokine system [LiteratureReference:208386] An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phosphorylated HOP phosphorylates DOME
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-DME-206942] Phospho HOP:Phospho DOME:UPD:Phospho DOME:Phospho HOP [plasma membrane]
precedingEvent	[Reaction:R-DME-209336] Activated HOP is autophosphorylated and/or transphosphorylated - Drosophila melanogaster
releaseDate	2009-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:386947] Perrimon, N, 2008-01-16 11:04:04
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-209160
summation	[Summation:206530] Tyr966 on the cytoplasmic tail of the DOME receptor is phosp...

Referrals

(hasEvent)	[Pathway:R-DME-209209] Formation of the activated receptor complex
(precedingEvent)	[Reaction:R-DME-209361] STAT92E binds to phosphorylated HOP and phosphorylated DOME

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