Reactome | nsp1 [cytosol]

Schema > DefinedSet > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9728782] PPIase:nsp1 [cytosol] - Homo sapiens [Complex:R-HSA-9729228] 40S ribosomal complex:nsp1 [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9728804] SARS-CoV-1 nsp1 binds to PPIase - Homo sapiens [Reaction:R-HSA-9728776] SARS-CoV-1 nsp1 binds to RCAN3 - Homo sapiens [Reaction:R-HSA-9729232] SARS-CoV-1 nsp1 binds to 40S ribosomal subunit - Homo sapiens
created	[InstanceEdit:9682209] Orlic-Milacic, Marija, 2020-04-08
crossReference	[DatabaseIdentifier:12020764] Mondo:0005091
dbId	9682210
disease	[Disease:9678120] severe acute respiratory syndrome
displayName	nsp1 [cytosol]
hasMember	[EntityWithAccessionedSequence:R-COV-9678243] pp1a-nsp1 [cytosol] - Human SARS coronavirus [EntityWithAccessionedSequence:R-COV-9682211] pp1ab-nsp1 [cytosol] - Human SARS coronavirus
inDisease	true
inferredTo	[DefinedSet:R-COV-9694741] nsp1 [cytosol] - Severe acute respiratory syndrome coronavirus 2
maxDepth	2
modified	[InstanceEdit:9689453] Orlic-Milacic, Marija, 2020-05-19
name	nsp1 Host translation inhibitor nsp1 pp1a-nsp1,pp1ab-nsp1
producedByEvent	[Reaction:R-HSA-9684321] nsp3 cleaves nsp1-4 - Homo sapiens [Reaction:R-HSA-9684336] nsp1-4 cleaves itself - Homo sapiens
schemaClass	DefinedSet
species	[Species:9678119] Human SARS coronavirus
stId	R-COV-9682210

(hasComponent)	[Complex:R-HSA-9729228] 40S ribosomal complex:nsp1 [cytosol] [Complex:R-HSA-9728782] PPIase:nsp1 [cytosol] [Complex:R-HSA-9728774] RCAN3:nsp1 [cytosol]
(input)	[Reaction:R-HSA-9729232] SARS-CoV-1 nsp1 binds to 40S ribosomal subunit [Reaction:R-HSA-9728804] SARS-CoV-1 nsp1 binds to PPIase [Reaction:R-HSA-9728776] SARS-CoV-1 nsp1 binds to RCAN3
(output)	[Reaction:R-HSA-9684321] nsp3 cleaves nsp1-4 [Reaction:R-HSA-9684336] nsp1-4 cleaves itself