Reactome | SARS-CoV-1 nsp1 binds to PPIase

Schema > Reaction > Entries

authored	[InstanceEdit:9728803] Stephan, Ralf, 2021-04-21
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9728796] Stephan, Ralf, 2021-04-22
crossReference	[DatabaseIdentifier:12020764] Mondo:0005091
dbId	9728804
disease	[Disease:9678120] severe acute respiratory syndrome
displayName	SARS-CoV-1 nsp1 binds to PPIase
edited	[InstanceEdit:9815358] Stephan, Ralf, 2022-08-17
eventOf	[Pathway:R-HSA-9692916] SARS-CoV-1 activates/modulates innate immune responses - Homo sapiens
input	[DefinedSet:R-COV-9682210] nsp1 [cytosol] [DefinedSet:R-HSA-9728790] PPIase [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9728773] The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors [LiteratureReference:9728787] Role for nonstructural protein 1 of severe acute respiratory syndrome coronavirus in chemokine dysregulation
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SARS-CoV-1 nsp1 binds to PPIase
output	[Complex:R-HSA-9728782] PPIase:nsp1 [cytosol]
precedingEvent	[Reaction:R-HSA-9684336] nsp1-4 cleaves itself - Homo sapiens
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2022-09-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9713569] D'Eustachio, Peter, 2021-01-26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9728804
summation	[Summation:9728792] Peptidyl-prolyl isomerases (PPIase) function as protein fold...

(hasEvent)

Cite Us!