Reactome | Ub:UBE2L3 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-CFA-9793473] RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] - Canis familiaris [Complex:R-CFA-8938767] RNF144A:PRKDC:Ub:UBE2L3 [cytosol] - Canis familiaris
consumedByEvent	[BlackBoxEvent:R-CFA-9817362] SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex - Canis familiaris [BlackBoxEvent:R-CFA-9793679] LUBAC ubiquitinates RIPK1 at K627 - Canis familiaris [BlackBoxEvent:R-CFA-8938773] RNF144A polyubiquitinates PRKDC - Canis familiaris [BlackBoxEvent:R-CFA-8938773] RNF144A polyubiquitinates PRKDC - Canis familiaris [Reaction:R-CFA-8938770] RNF144A binds PRKDC and Ubiquitin:UBE2L3 - Canis familiaris [Reaction:R-CFA-9794008] LUBAC binds CFLAR - Canis familiaris [Reaction:R-CFA-9793472] RIPK3 binds p-S9-PRKN - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10311884
displayName	Ub:UBE2L3 [cytosol]
hasComponent	[DefinedSet:R-CFA-113595] Ub [cytosol] [EntityWithAccessionedSequence:R-CFA-8864201] UBE2L3 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8938763] Ub:UBE2L3 [cytosol] - Homo sapiens
maxDepth	3
name	Ub:UBE2L3
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-8938763
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-CFA-8938773] RNF144A polyubiquitinates PRKDC [Reaction:R-CFA-8938770] RNF144A binds PRKDC and Ubiquitin:UBE2L3 [Reaction:R-CFA-9794008] LUBAC binds CFLAR [BlackBoxEvent:R-CFA-9817362] SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex [BlackBoxEvent:R-CFA-9793679] LUBAC ubiquitinates RIPK1 at K627 [Reaction:R-CFA-9793472] RIPK3 binds p-S9-PRKN
(hasComponent)	[Complex:R-CFA-8938767] RNF144A:PRKDC:Ub:UBE2L3 [cytosol] [Complex:R-CFA-9794013] CFLAR:LUBAC:Ub:UBE2D3 [cytosol] [Complex:R-CFA-9793473] RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] [Complex:R-CFA-9793452] p-S-RIPK1:p-S-RIPK3:p-T,S-MLKL:ITCH:Ub:UBE2L3 [cytosol]
(inferredTo)	[Complex:R-HSA-8938763] Ub:UBE2L3 [cytosol]

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