Reactome | TAF1 phosphorylates TP53

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TAF1 phosphorylates TP53 Show undefined attributes

catalystActivity	[CatalystActivity:10303840] protein serine/threonine kinase activity of TFIID [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10303842
displayName	TAF1 phosphorylates TP53
eventOf	[Pathway:R-CFA-6804756] Regulation of TP53 Activity through Phosphorylation - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6805399] TAF1 phosphorylates TP53 - Homo sapiens
input	4 × [SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-CFA-3209194] TP53 Tetramer [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	TAF1 phosphorylates TP53
output	4 × [SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-CFA-6805395] p-T55-TP53 Tetramer [nucleoplasm]
precedingEvent	[Reaction:R-CFA-6804762] TP53 forms homotetramers - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-6805399
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-6804756] Regulation of TP53 Activity through Phosphorylation
(inferredTo)	[Reaction:R-HSA-6805399] TAF1 phosphorylates TP53

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