Reactome | SYK [cytosol]

Schema > EntityWithAccessionedSequence > Entries

SYK [cytosol] Show undefined attributes

candidateOf	[CandidateSet:R-CFA-912625] FYN-like kinases [cytosol] - Canis familiaris
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-CFA-508449] IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] - Canis familiaris [Complex:R-CFA-9706276] active FLT3:SYK [plasma membrane] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-5621366] SYK binds to p-Y65,Y76-FCER1G - Canis familiaris [Reaction:R-CFA-210289] Recruitment of SYK to p-DAP12 - Canis familiaris [Reaction:R-CFA-9706336] Active FLT3 binds to SYK - Canis familiaris [Reaction:R-CFA-5684801] p-Y7-CLEC1B dimer:PDPN binds SYK - Canis familiaris [Reaction:R-CFA-429415] SYK binds to integrin alphaIIb beta3 - Canis familiaris [Reaction:R-CFA-429415] SYK binds to integrin alphaIIb beta3 - Canis familiaris [Reaction:R-CFA-508292] SYK binds IL2RB - Canis familiaris [Reaction:R-CFA-2454240] Recruitment of SYK to p-FCERI gamma subunit - Canis familiaris [Reaction:R-CFA-983700] SYK binds the activated BCR - Canis familiaris [Reaction:R-CFA-139842] Binding of Syk tyrosine kinase - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10235016
displayName	SYK [cytosol]
endCoordinate	635
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-58268] SYK [cytosol] - Homo sapiens
maxDepth	1
name	SYK SYK A0A8I3P3G0
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8I3P3G0] UniProt:A0A8I3P3G0
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49646] Canis familiaris
stId	R-CFA-58268
startCoordinate	1

Referrals

(input)	[Reaction:R-CFA-9706336] Active FLT3 binds to SYK [Reaction:R-CFA-5684801] p-Y7-CLEC1B dimer:PDPN binds SYK [Reaction:R-CFA-429415] SYK binds to integrin alphaIIb beta3 [Reaction:R-CFA-508292] SYK binds IL2RB [Reaction:R-CFA-5621366] SYK binds to p-Y65,Y76-FCER1G [Reaction:R-CFA-2454240] Recruitment of SYK to p-FCERI gamma subunit [Reaction:R-CFA-210289] Recruitment of SYK to p-DAP12 [Reaction:R-CFA-983700] SYK binds the activated BCR [Reaction:R-CFA-139842] Binding of Syk tyrosine kinase
(hasComponent)	[Complex:R-CFA-9706276] active FLT3:SYK [plasma membrane] [Complex:R-CFA-429424] Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] [Complex:R-CFA-508449] IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] [Complex:R-CFA-5621149] pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:SYK [plasma membrane] [Complex:R-CFA-2454243] Clustered p:LYN:p-FCERI:IgE:allergen:SYK [plasma membrane] [Complex:R-CFA-210250] DAP12 receptors:p-DAP12:SYK [plasma membrane] [Complex:R-CFA-983693] Antigen:p-BCR:SYK [plasma membrane] [Complex:R-CFA-434911] GPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:SYK [plasma membrane] [Complex:R-CFA-5684799] p-Y7-CLEC1B dimer:PDPN:SYK [plasma membrane]
(hasCandidate)	[CandidateSet:R-CFA-912625] FYN-like kinases [cytosol]
(activeUnit)	[CatalystActivity:10278880] protein tyrosine kinase activity of DAP12 receptors:p-DAP12:SYK [plasma membrane] [CatalystActivity:10259131] non-membrane spanning protein tyrosine kinase activity of GPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:SYK [plasma membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-58268] SYK [cytosol]

© 2026 Reactome

Cite Us!