Reactome | IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10259955] protein tyrosine kinase activity of IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-CFA-508282] SYK is a substrate for JAK1 - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10259952
displayName	IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane]
hasComponent	[Complex:R-CFA-451920] IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] [EntityWithAccessionedSequence:R-CFA-58268] SYK [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-508449] IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] - Homo sapiens
maxDepth	6
name	IL2:IL2R trimer:p-JAK1:JAK3:SYK
producedByEvent	[Reaction:R-CFA-508292] SYK binds IL2RB - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-508449
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-CFA-508282] SYK is a substrate for JAK1
(physicalEntity)	[CatalystActivity:10259955] protein tyrosine kinase activity of IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane]
(output)	[Reaction:R-CFA-508292] SYK binds IL2RB
(inferredTo)	[Complex:R-HSA-508449] IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane]

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