Reactome | RHOA:GDP [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-CEL-9012835] GDIs block activation of RHOA - Caenorhabditis elegans [Reaction:R-CEL-8980691] RHOA GEFs activate RHOA - Caenorhabditis elegans [Reaction:R-CEL-114544] p115-RhoGEF activation of RHOA - Caenorhabditis elegans [Reaction:R-CEL-194518] RhoA is activated by nucleotide exchange and inhibits axonal growth - Caenorhabditis elegans [Reaction:R-CEL-3928651] NGEF exchanges GTP for GDP on RHOA - Caenorhabditis elegans [Reaction:R-CEL-3928592] p190RhoGEF exchanges GTP for GDP on RHOA, activating it - Caenorhabditis elegans
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10921785
displayName	RHOA:GDP [plasma membrane]
hasComponent	[SimpleEntity:R-ALL-29420] GDP [cytosol] [EntityWithAccessionedSequence:R-CEL-194510] RHOA [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8964174] RHOA:GDP [plasma membrane] - Homo sapiens
maxDepth	2
name	RHOA:GDP
producedByEvent	[Reaction:R-CEL-8981637] RHOA GAPs stimulate RHOA GTPase activity - Caenorhabditis elegans [Reaction:R-CEL-8985594] MYO9B inactivates RHOA - Caenorhabditis elegans [Reaction:R-CEL-8849082] ARHGAP35 stimulates RHOA GTPase activity - Caenorhabditis elegans
schemaClass	Complex
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-8964174
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-CEL-8981637] RHOA GAPs stimulate RHOA GTPase activity [Reaction:R-CEL-8985594] MYO9B inactivates RHOA [Reaction:R-CEL-8849082] ARHGAP35 stimulates RHOA GTPase activity
(input)	[Reaction:R-CEL-9012835] GDIs block activation of RHOA [Reaction:R-CEL-8980691] RHOA GEFs activate RHOA [Reaction:R-CEL-114544] p115-RhoGEF activation of RHOA [Reaction:R-CEL-3928592] p190RhoGEF exchanges GTP for GDP on RHOA, activating it [Reaction:R-CEL-194518] RhoA is activated by nucleotide exchange and inhibits axonal growth [Reaction:R-CEL-3928651] NGEF exchanges GTP for GDP on RHOA
(inferredTo)	[Complex:R-HSA-8964174] RHOA:GDP [plasma membrane]

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