Reactome | MYO9B inactivates RHOA

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MYO9B inactivates RHOA Show undefined attributes

catalystActivity	[CatalystActivity:10985962] GTPase activator activity of MYO9B [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10985964
displayName	MYO9B inactivates RHOA
eventOf	[Pathway:R-CEL-8985586] SLIT2:ROBO1 increases RHOA activity - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8985594] MYO9B inactivates RHOA - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-CEL-5665993] RHOA:GTP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	MYO9B inactivates RHOA
output	[SimpleEntity:R-ALL-29372] Pi [cytosol] [Complex:R-CEL-8964174] RHOA:GDP [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-8985594
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-8985586] SLIT2:ROBO1 increases RHOA activity
(inferredTo)	[Reaction:R-HSA-8985594] MYO9B inactivates RHOA

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