Reactome | Fatty acyl-CoA biosynthesis

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Fatty acyl-CoA biosynthesis Show undefined attributes

compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10993689
displayName	Fatty acyl-CoA biosynthesis
eventOf	[Pathway:R-CEL-8978868] Fatty acid metabolism - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:78809] fatty-acyl-CoA biosynthetic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-CEL-75848] ACLY tetramer transforms CIT to Ac-CoA - Caenorhabditis elegans [Reaction:R-CEL-9734535] SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA - Caenorhabditis elegans [Reaction:R-CEL-9734540] ACLY tetramer binds ETC-1002-CoA - Caenorhabditis elegans [Reaction:R-CEL-200555] Formation of Malonyl-CoA from Acetyl-CoA (liver) - Caenorhabditis elegans [Reaction:R-CEL-163756] Formation of fatty acid synthase (FAS) dimer - Caenorhabditis elegans [Reaction:R-CEL-75872] Conversion of malonyl-CoA and acetyl-CoA to palmitate - Caenorhabditis elegans [Pathway:R-CEL-75876] Synthesis of very long-chain fatty acyl-CoAs - Caenorhabditis elegans [Reaction:R-CEL-5690565] SCD desaturates ST-CoA to OLE-CoA - Caenorhabditis elegans [Reaction:R-CEL-8847579] SCD5 desaturates ST-CoA to OLE-CoA - Caenorhabditis elegans [Reaction:R-CEL-5690517] PPT1 hydrolyses palmitoylated proteins - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-75105] Fatty acyl-CoA biosynthesis - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Fatty acyl-CoA biosynthesis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-75105
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-8978868] Fatty acid metabolism
(inferredTo)	[Pathway:R-HSA-75105] Fatty acyl-CoA biosynthesis