Reactome | EIF4G1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-BTA-927743] mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] - Bos taurus [Complex:R-BTA-429977] Translatable mRNA Complex [cytosol] - Bos taurus [Complex:R-BTA-450623] AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] - Bos taurus [Complex:R-BTA-927845] mRNA Cleaved by SMG6 [cytosol] - Bos taurus
consumedByEvent	[Reaction:R-BTA-165766] Phosphorylation and activation of eIF4G by activated S6K1 - Bos taurus [Reaction:R-BTA-450551] AUF1 binds translation and heat shock proteins - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10336071
displayName	EIF4G1 [cytosol]
endCoordinate	1599
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-72584] EIF4G1 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-BTA-1678828] EIF4G [cytosol] - Bos taurus
name	EIF4G1 EIF4G1 F1MX04
producedByEvent	[BlackBoxEvent:R-BTA-927830] Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex - Bos taurus [Reaction:R-BTA-429992] PARN deadenylates mRNA - Bos taurus [Reaction:R-BTA-429955] CCR4-NOT complex deadenylates mRNA - Bos taurus
referenceEntity	[ReferenceGeneProduct:uniprot:F1MX04] UniProt:F1MX04
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48898] Bos taurus
stId	R-BTA-72584
startCoordinate	1

(input)	[Reaction:R-BTA-450551] AUF1 binds translation and heat shock proteins [Reaction:R-BTA-165766] Phosphorylation and activation of eIF4G by activated S6K1
(hasComponent)	[Complex:R-BTA-450623] AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] [Complex:R-BTA-927845] mRNA Cleaved by SMG6 [cytosol] [Complex:R-BTA-927743] mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] [Complex:R-BTA-927823] mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] [Complex:R-BTA-429977] Translatable mRNA Complex [cytosol] [Complex:R-BTA-429989] Partially Deadenylated mRNA Complex [cytosol] [Complex:R-BTA-72587] eIF4F [cytosol]
(output)	[BlackBoxEvent:R-BTA-927830] Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex [Reaction:R-BTA-429992] PARN deadenylates mRNA [Reaction:R-BTA-429955] CCR4-NOT complex deadenylates mRNA
(hasMember)	[DefinedSet:R-BTA-1678828] EIF4G [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-72584] EIF4G1 [cytosol]