Reactome | FADD [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-BTA-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] - Bos taurus [Complex:R-BTA-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] - Bos taurus [Complex:R-BTA-43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] - Bos taurus [Complex:R-BTA-43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] - Bos taurus [Complex:R-BTA-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] - Bos taurus [Complex:R-BTA-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] - Bos taurus
consumedByEvent	[Reaction:R-BTA-83650] FasL:Fas binds FADD - Bos taurus [Reaction:R-BTA-83650] FasL:Fas binds FADD - Bos taurus [Reaction:R-BTA-140978] TRADD:TRAF2:RIP1 binds FADD - Bos taurus [Reaction:R-BTA-140978] TRADD:TRAF2:RIP1 binds FADD - Bos taurus [Reaction:R-BTA-2562541] TLR4-induced ripoptosome assembly - Bos taurus [Reaction:R-BTA-2562541] TLR4-induced ripoptosome assembly - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10337117
displayName	FADD [cytosol]
endCoordinate	208
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-54639] FADD [cytosol] - Homo sapiens
maxDepth	1
name	FADD FADD Q645M6
referenceEntity	[ReferenceGeneProduct:uniprot:Q645M6] UniProt:Q645M6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48898] Bos taurus
stId	R-BTA-54639
startCoordinate	1

(hasComponent)	[Complex:R-BTA-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] [Complex:R-BTA-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] [Complex:R-BTA-43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] [Complex:R-BTA-140977] TRADD:TRAF2:RIPK1:FADD [cytosol] [Complex:R-BTA-2562577] activated TLR4:TRIF:RIP1:FADD [endosome membrane] [Complex:R-BTA-2562542] activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane]
(input)	[Reaction:R-BTA-83650] FasL:Fas binds FADD [Reaction:R-BTA-140978] TRADD:TRAF2:RIP1 binds FADD [Reaction:R-BTA-2562541] TLR4-induced ripoptosome assembly
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-54639] FADD [cytosol]