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BCL2 [mitochondrial outer membrane]
Stable Identifier
R-BTA-50757
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
mitochondrial outer membrane
Synonyms
BCL2, F6R2C4
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Bos taurus)
Inflammasomes (Bos taurus)
The NLRP1 inflammasome (Bos taurus)
Bcl-2 and Bcl-XL bind NLRP1 (Bos taurus)
Bcl-2/Bcl-X(L) [mitochondrial outer membrane] (Bos taurus)
BCL2 [mitochondrial outer membrane] (Bos taurus)
Bcl-2/Bcl-X(L):NLRP1 [mitochondrial outer membrane] (Bos taurus)
Bcl-2/Bcl-X(L) [mitochondrial outer membrane] (Bos taurus)
BCL2 [mitochondrial outer membrane] (Bos taurus)
Programmed Cell Death (Bos taurus)
Apoptosis (Bos taurus)
Intrinsic Pathway for Apoptosis (Bos taurus)
Activation of BH3-only proteins (Bos taurus)
Activation of BAD and translocation to mitochondria (Bos taurus)
BAD displaces tBID from BCL-2 sequestration (Bos taurus)
BAD:BCL-2 [mitochondrial outer membrane] (Bos taurus)
BCL2 [mitochondrial outer membrane] (Bos taurus)
tBID:BCL-2 [mitochondrial outer membrane] (Bos taurus)
BCL2 [mitochondrial outer membrane] (Bos taurus)
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members (Bos taurus)
BCL2 binds BCL2 antagonists (Bos taurus)
BCL2 [mitochondrial outer membrane] (Bos taurus)
BCL2:BCL2 antagonists [mitochondrial outer membrane] (Bos taurus)
BCL2 [mitochondrial outer membrane] (Bos taurus)
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 (Bos taurus)
BCL2 [mitochondrial outer membrane] (Bos taurus)
Bcl2:BH3-only protein complex [mitochondrial outer membrane] (Bos taurus)
BCL2 [mitochondrial outer membrane] (Bos taurus)
Sequestration of tBID by BCL-2 (Bos taurus)
BCL2 [mitochondrial outer membrane] (Bos taurus)
tBID:BCL-2 [mitochondrial outer membrane] (Bos taurus)
BCL2 [mitochondrial outer membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:F6R2C4
Gene Names
BCL2
Reference Genes
BioGPS Gene:281020 BCL2
ENSEMBL:ENSBTAG00000019302.6
ENSEMBL:ENSBTAG00000019302.7 BCL2
KEGG Gene (Bos taurus):281020 BCL2
Monarch:281020 BCL2
NCBI Gene:281020 BCL2
Reference Transcript
RefSeq:NM_001166486.1 BCL2
Other Identifiers
281020
GO:0005634
GO:0005635
GO:0005737
GO:0005739
GO:0005741
GO:0005783
GO:0005789
GO:0006915
GO:0008630
GO:0012501
GO:0016020
GO:0023052
GO:0031965
GO:0042803
GO:0042981
GO:0043066
GO:0043226
GO:0046982
GO:0097192
GO:2001243
Participates
as an input of
BCL2 binds BCL2 antagonists (Bos taurus)
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 (Bos taurus)
Sequestration of tBID by BCL-2 (Bos taurus)
as a component of
BCL2:BCL2 antagonists [mitochondrial outer membrane] (Bos taurus)
Bcl2:BH3-only protein complex [mitochondrial outer membrane] (Bos taurus)
BAD:BCL-2 [mitochondrial outer membrane] (Bos taurus)
tBID:BCL-2 [mitochondrial outer membrane] (Bos taurus)
as a member of
Bcl-2/Bcl-X(L) [mitochondrial outer membrane] (Bos taurus)
Inferred From
BCL2 [mitochondrial outer membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001159958.1
OpenTargets
ENSG00000171791
Ensembl
ENSBTAT00000025701
,
ENSBTAG00000019302
,
ENSBTAP00000025701
VGNC
26445
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