Reactome | p-T,Y MAPK dimers [cytosol]

Schema > DefinedSet > Entries

p-T,Y MAPK dimers [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:10403145] MAP kinase activity of p-T,Y MAPK dimers [cytosol] [CatalystActivity:10385303] protein serine/threonine kinase activity of p-T,Y MAPK dimers [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-BTA-9635740] PTPN7:p-T,Y-MAPK dimers [cytosol] - Bos taurus
consumedByEvent	[BlackBoxEvent:R-BTA-9610166] p-T,Y MAPK dimers translocate to nucleus - Bos taurus [Reaction:R-BTA-9635743] PTPN7 binds p-T,Y-MAPK - Bos taurus [Reaction:R-BTA-6811472] IER3 recruits MAPKs to PP2A-B56-beta,gamma - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10346148
displayName	p-T,Y MAPK dimers [cytosol]
hasMember	[Complex:R-BTA-109844] p-T202, Y204 MAPK3 dimer [cytosol] - Bos taurus [Complex:R-BTA-109855] p-T185,Y187 MAPK1 dimer [cytosol] - Bos taurus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-1268261] p-T,Y MAPK dimers [cytosol] - Homo sapiens
isRequired	[Requirement:10376183] Requirement by 'p-T,Y MAPK dimers [cytosol]'
maxDepth	3
memberOf	[DefinedSet:R-BTA-5674340] p-T,Y MAPK monomers and dimers [cytosol] - Bos taurus
name	p-T,Y MAPK dimers p-ERK dimer
negativelyRegulates	[NegativeRegulation:10346151] Negative regulation by 'p-T,Y MAPK dimers [cytosol]'
positivelyRegulates	[Requirement:10376183] Requirement by 'p-T,Y MAPK dimers [cytosol]'
producedByEvent	[BlackBoxEvent:R-BTA-9732753] JAK1-activated RAF1 phosphorylates MAPKs - Bos taurus [Reaction:R-BTA-5674385] p-T,Y MAPKs dimerize - Bos taurus [Reaction:R-BTA-6811454] MAPKs phosphorylate PP2A - Bos taurus
schemaClass	DefinedSet
species	[Species:48898] Bos taurus
stId	R-BTA-1268261

Referrals

(regulator)	[Requirement:10376183] Requirement by 'p-T,Y MAPK dimers [cytosol]' [NegativeRegulation:10346151] Negative regulation by 'p-T,Y MAPK dimers [cytosol]'
(physicalEntity)	[CatalystActivity:10403145] MAP kinase activity of p-T,Y MAPK dimers [cytosol] [CatalystActivity:10385303] protein serine/threonine kinase activity of p-T,Y MAPK dimers [cytosol]
(input)	[Reaction:R-BTA-9635743] PTPN7 binds p-T,Y-MAPK [Reaction:R-BTA-6811472] IER3 recruits MAPKs to PP2A-B56-beta,gamma [BlackBoxEvent:R-BTA-9610166] p-T,Y MAPK dimers translocate to nucleus
(hasComponent)	[Complex:R-BTA-9635740] PTPN7:p-T,Y-MAPK dimers [cytosol] [Complex:R-BTA-6811477] PP2A-B56-beta,gamma:IER3:p-T,Y-MAPK dimers [cytosol]
(output)	[Reaction:R-BTA-6811454] MAPKs phosphorylate PP2A [BlackBoxEvent:R-BTA-9732753] JAK1-activated RAF1 phosphorylates MAPKs [Reaction:R-BTA-5674385] p-T,Y MAPKs dimerize
(activeUnit)	[CatalystActivity:10418716] protein serine/threonine kinase activity of PP2A-B56-beta,gamma:IER3:p-T,Y-MAPK dimers [cytosol]
(hasMember)	[DefinedSet:R-BTA-5674340] p-T,Y MAPK monomers and dimers [cytosol]
(inferredTo)	[DefinedSet:R-HSA-1268261] p-T,Y MAPK dimers [cytosol]