Reactome | IL6ST:JAK1, JAK2, (TYK2) [plasma membrane]

Schema > Complex > Entries

IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-BTA-8983525] IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] - Bos taurus [Complex:R-BTA-8983525] IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] - Bos taurus [Complex:R-BTA-6809138] IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] - Bos taurus
consumedByEvent	[BlackBoxEvent:R-BTA-8983518] IL35 binds IL6ST:IL6ST receptor - Bos taurus [BlackBoxEvent:R-BTA-8983518] IL35 binds IL6ST:IL6ST receptor - Bos taurus [Reaction:R-BTA-448427] Interleukin-27 binds Interleukin-27 receptor - Bos taurus [Reaction:R-BTA-6783530] gp130:JAKs bind CNTFR - Bos taurus [Reaction:R-BTA-1067688] IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) - Bos taurus [Reaction:R-BTA-1067651] IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) - Bos taurus [BlackBoxEvent:R-BTA-6809140] IL35 binds IL-12RB2:IL6ST receptor - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10365874
displayName	IL6ST:JAK1, JAK2, (TYK2) [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-BTA-448453] IL6ST [plasma membrane] [CandidateSet:R-BTA-1067656] JAK1, JAK2, (TYK2) [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-1067690] IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] - Homo sapiens
maxDepth	3
name	IL6ST:JAK1, JAK2, (TYK2)
producedByEvent	[Reaction:R-BTA-8950210] Interleukin-27 dissociates from Interleukin-27 receptor - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-1067690
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[BlackBoxEvent:R-BTA-8983518] IL35 binds IL6ST:IL6ST receptor [BlackBoxEvent:R-BTA-6809140] IL35 binds IL-12RB2:IL6ST receptor [Reaction:R-BTA-448427] Interleukin-27 binds Interleukin-27 receptor [Reaction:R-BTA-6783530] gp130:JAKs bind CNTFR [Reaction:R-BTA-1067688] IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) [Reaction:R-BTA-1067651] IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2)
(hasComponent)	[Complex:R-BTA-8983525] IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] [Complex:R-BTA-6809138] IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] [Complex:R-BTA-448431] IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] [Complex:R-BTA-6783658] CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] [Complex:R-BTA-1067691] IL6:sIL6R:IL6RB:JAKs [plasma membrane] [Complex:R-BTA-1067654] IL6:IL6RA:IL6RB:JAKs [plasma membrane]
(output)	[Reaction:R-BTA-8950210] Interleukin-27 dissociates from Interleukin-27 receptor
(inferredTo)	[Complex:R-HSA-1067690] IL6ST:JAK1, JAK2, (TYK2) [plasma membrane]

© 2026 Reactome

Cite Us!