Reactome | IL6:sIL6R:IL6RB:JAKs [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10374640
displayName	IL6:sIL6R:IL6RB:JAKs [plasma membrane]
hasComponent	[Complex:R-BTA-1067687] IL6:IL6R-2 [extracellular region] [Complex:R-BTA-1067690] IL6ST:JAK1, JAK2, (TYK2) [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-1067691] IL6:sIL6R:IL6RB:JAKs [plasma membrane] - Homo sapiens
maxDepth	4
memberOf	[DefinedSet:R-BTA-1112523] IL6 receptor trimer:JAKs [plasma membrane] - Bos taurus
name	IL6:sIL6R:IL6RB:JAKs
producedByEvent	[Reaction:R-BTA-1067651] IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-1067691
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-BTA-1067651] IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2)
(hasMember)	[DefinedSet:R-BTA-1112523] IL6 receptor trimer:JAKs [plasma membrane]
(inferredTo)	[Complex:R-HSA-1067691] IL6:sIL6R:IL6RB:JAKs [plasma membrane]

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