Reactome | HCQ [cytosol]

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HCQ [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-9678617] C-ter TLR7 dimer:HCQ [endosome membrane] - Rattus norvegicus [Complex:R-MMU-9678655] C-ter TLR9 dimer:HCQ [endosome membrane] - Mus musculus
consumedByEvent	[Reaction:R-GGA-9679029] C-ter TLR7 dimer binds HCQ - Gallus gallus [Reaction:R-XTR-9679029] C-ter TLR7 dimer binds HCQ - Xenopus tropicalis [Reaction:R-SSC-9679029] C-ter TLR7 dimer binds HCQ - Sus scrofa [Reaction:R-BTA-9679029] C-ter TLR7 dimer binds HCQ - Bos taurus [Reaction:R-CFA-9679029] C-ter TLR7 dimer binds HCQ - Canis familiaris [Reaction:R-MMU-9679029] C-ter TLR7 dimer binds HCQ - Mus musculus [Reaction:R-HSA-9679029] C-ter TLR7 dimer binds HCQ - Homo sapiens [Reaction:R-RNO-9679029] C-ter TLR7 dimer binds HCQ - Rattus norvegicus [Reaction:R-SSC-9679045] C-ter TLR9 dimer binds HCQ - Sus scrofa [Reaction:R-BTA-9679045] C-ter TLR9 dimer binds HCQ - Bos taurus [Reaction:R-CFA-9679045] C-ter TLR9 dimer binds HCQ - Canis familiaris [Reaction:R-MMU-9679045] C-ter TLR9 dimer binds HCQ - Mus musculus [Reaction:R-HSA-9679045] C-ter TLR9 dimer binds HCQ - Homo sapiens [Reaction:R-RNO-9679045] C-ter TLR9 dimer binds HCQ - Rattus norvegicus
created	[InstanceEdit:9678968] Jassal, Bijay, 2020-03-23
dbId	9678628
disease	[Disease:9660981] malaria [Disease:9625952] systemic lupus erythematosus
displayName	HCQ [cytosol]
inDisease	true
memberOf	[DefinedSet:R-ALL-9685614] CQ, HCQ [cytosol]
modified	[InstanceEdit:9684971] Jassal, Bijay, 2020-04-22
name	HCQ hydroxychloroquine Dolquine® Plaquenil®
referenceEntity	[ReferenceTherapeutic:9678830] hydroxychloroquine [Guide to Pharmacology:7198]
schemaClass	ChemicalDrug
stId	R-ALL-9678628

Referrals

(hasMember)	[DefinedSet:R-ALL-9685614] CQ, HCQ [cytosol]
(input)	[Reaction:R-GGA-9679029] C-ter TLR7 dimer binds HCQ [Reaction:R-XTR-9679029] C-ter TLR7 dimer binds HCQ [Reaction:R-SSC-9679029] C-ter TLR7 dimer binds HCQ [Reaction:R-BTA-9679029] C-ter TLR7 dimer binds HCQ [Reaction:R-CFA-9679029] C-ter TLR7 dimer binds HCQ [Reaction:R-MMU-9679029] C-ter TLR7 dimer binds HCQ [Reaction:R-HSA-9679029] C-ter TLR7 dimer binds HCQ [Reaction:R-RNO-9679029] C-ter TLR7 dimer binds HCQ [Reaction:R-SSC-9679045] C-ter TLR9 dimer binds HCQ [Reaction:R-BTA-9679045] C-ter TLR9 dimer binds HCQ [Reaction:R-CFA-9679045] C-ter TLR9 dimer binds HCQ [Reaction:R-MMU-9679045] C-ter TLR9 dimer binds HCQ [Reaction:R-HSA-9679045] C-ter TLR9 dimer binds HCQ [Reaction:R-RNO-9679045] C-ter TLR9 dimer binds HCQ
(hasComponent)	[Complex:R-MMU-9678655] C-ter TLR9 dimer:HCQ [endosome membrane] [Complex:R-RNO-9678655] C-ter TLR9 dimer:HCQ [endosome membrane] [Complex:R-SSC-9678655] C-ter TLR9 dimer:HCQ [endosome membrane] [Complex:R-CFA-9678655] C-ter TLR9 dimer:HCQ [endosome membrane] [Complex:R-BTA-9678655] C-ter TLR9 dimer:HCQ [endosome membrane] [Complex:R-HSA-9678655] C-ter TLR9 dimer:HCQ [endosome membrane] [Complex:R-RNO-9678617] C-ter TLR7 dimer:HCQ [endosome membrane] [Complex:R-XTR-9678617] C-ter TLR7 dimer:HCQ [endosome membrane] [Complex:R-BTA-9678617] C-ter TLR7 dimer:HCQ [endosome membrane] [Complex:R-GGA-9678617] C-ter TLR7 dimer:HCQ [endosome membrane] [Complex:R-SSC-9678617] C-ter TLR7 dimer:HCQ [endosome membrane] [Complex:R-CFA-9678617] C-ter TLR7 dimer:HCQ [endosome membrane] [Complex:R-MMU-9678617] C-ter TLR7 dimer:HCQ [endosome membrane] [Complex:R-HSA-9678617] C-ter TLR7 dimer:HCQ [endosome membrane]

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