Reactome | ACA [cytosol]

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ACA [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-CEL-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA - Caenorhabditis elegans [Reaction:R-GGA-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA - Gallus gallus [Reaction:R-DRE-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA - Danio rerio [Reaction:R-SSC-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA - Sus scrofa [Reaction:R-BTA-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA - Bos taurus [Reaction:R-RNO-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA - Rattus norvegicus [Reaction:R-MMU-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA - Mus musculus [Reaction:R-HSA-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA - Homo sapiens
crossReference	[DatabaseIdentifier:29667] COMPOUND:C00164
dbId	29666
displayName	ACA [cytosol]
inDisease	false
maxDepth	1
memberOf	[DefinedSet:R-ALL-433686] MCT substrates [cytosol]
modified	[InstanceEdit:9619952] Wu, G, 2018-09-19
name	ACA 3-Oxobutanoate acetoacetate
producedByEvent	[Reaction:R-GGA-5696457] BDH2 dehydrogenates 3HBA - Gallus gallus [Reaction:R-XTR-5696457] BDH2 dehydrogenates 3HBA - Xenopus tropicalis [Reaction:R-DRE-5696457] BDH2 dehydrogenates 3HBA - Danio rerio [Reaction:R-SSC-5696457] BDH2 dehydrogenates 3HBA - Sus scrofa [Reaction:R-BTA-5696457] BDH2 dehydrogenates 3HBA - Bos taurus [Reaction:R-CFA-5696457] BDH2 dehydrogenates 3HBA - Canis familiaris [Reaction:R-RNO-5696457] BDH2 dehydrogenates 3HBA - Rattus norvegicus [Reaction:R-MMU-5696457] BDH2 dehydrogenates 3HBA - Mus musculus [Reaction:R-HSA-5696457] BDH2 dehydrogenates 3HBA - Homo sapiens [Reaction:R-DDI-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Dictyostelium discoideum [Reaction:R-CEL-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Caenorhabditis elegans [Reaction:R-DME-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Drosophila melanogaster [Reaction:R-GGA-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Gallus gallus [Reaction:R-XTR-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Xenopus tropicalis [Reaction:R-DRE-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Danio rerio [Reaction:R-SSC-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Sus scrofa [Reaction:R-BTA-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Bos taurus [Reaction:R-CFA-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Canis familiaris [Reaction:R-RNO-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Rattus norvegicus [Reaction:R-MMU-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Mus musculus [Reaction:R-HSA-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA - Homo sapiens [Reaction:R-DDI-71181] FAH cleaves 4FAA - Dictyostelium discoideum [Reaction:R-CEL-71181] FAH cleaves 4FAA - Caenorhabditis elegans [Reaction:R-DME-71181] FAH cleaves 4FAA - Drosophila melanogaster [Reaction:R-GGA-71181] FAH cleaves 4FAA - Gallus gallus [Reaction:R-XTR-71181] FAH cleaves 4FAA - Xenopus tropicalis [Reaction:R-SSC-71181] FAH cleaves 4FAA - Sus scrofa [Reaction:R-BTA-71181] FAH cleaves 4FAA - Bos taurus [Reaction:R-CFA-71181] FAH cleaves 4FAA - Canis familiaris [Reaction:R-MMU-71181] FAH cleaves 4FAA - Mus musculus [Reaction:R-HSA-71181] FAH cleaves 4FAA - Homo sapiens [Reaction:R-RNO-71181] FAH cleaves 4FAA - Rattus norvegicus
referenceEntity	[ReferenceMolecule:chebi:13705] acetoacetate [ChEBI:13705]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-29666
updateTrackers	[UpdateTracker:9873442] Update Tracker - [SimpleEntity:29666] ACA [cytosol] - v43:[addName] [UpdateTracker:9891234] Update Tracker - [SimpleEntity:29666] ACA [cytosol] - v52:[modifyName] [UpdateTracker:9869482] Update Tracker - [SimpleEntity:29666] ACA [cytosol] - v33:[add_removeReferenceEntity, modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9873442] Update Tracker - [SimpleEntity:29666] ACA [cytosol] - v43:[addName] [UpdateTracker:9891234] Update Tracker - [SimpleEntity:29666] ACA [cytosol] - v52:[modifyName] [UpdateTracker:9869482] Update Tracker - [SimpleEntity:29666] ACA [cytosol] - v33:[add_removeReferenceEntity, modifyName]
(input)	[Reaction:R-CEL-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA [Reaction:R-GGA-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA [Reaction:R-DRE-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA [Reaction:R-SSC-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA [Reaction:R-BTA-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA [Reaction:R-RNO-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA [Reaction:R-MMU-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA [Reaction:R-HSA-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA
(output)	[Reaction:R-GGA-5696457] BDH2 dehydrogenates 3HBA [Reaction:R-XTR-5696457] BDH2 dehydrogenates 3HBA [Reaction:R-DRE-5696457] BDH2 dehydrogenates 3HBA [Reaction:R-SSC-5696457] BDH2 dehydrogenates 3HBA [Reaction:R-BTA-5696457] BDH2 dehydrogenates 3HBA [Reaction:R-CFA-5696457] BDH2 dehydrogenates 3HBA [Reaction:R-RNO-5696457] BDH2 dehydrogenates 3HBA [Reaction:R-MMU-5696457] BDH2 dehydrogenates 3HBA [Reaction:R-HSA-5696457] BDH2 dehydrogenates 3HBA [Reaction:R-DDI-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-CEL-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-DME-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-GGA-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-XTR-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-DRE-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-SSC-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-BTA-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-CFA-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-RNO-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-MMU-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-HSA-6788597] HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA [Reaction:R-DDI-71181] FAH cleaves 4FAA [Reaction:R-CEL-71181] FAH cleaves 4FAA [Reaction:R-DME-71181] FAH cleaves 4FAA [Reaction:R-GGA-71181] FAH cleaves 4FAA [Reaction:R-XTR-71181] FAH cleaves 4FAA [Reaction:R-SSC-71181] FAH cleaves 4FAA [Reaction:R-BTA-71181] FAH cleaves 4FAA [Reaction:R-CFA-71181] FAH cleaves 4FAA [Reaction:R-MMU-71181] FAH cleaves 4FAA [Reaction:R-HSA-71181] FAH cleaves 4FAA [Reaction:R-RNO-71181] FAH cleaves 4FAA
(hasMember)	[DefinedSet:R-ALL-433686] MCT substrates [cytosol]

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