Reactome | BDH2 dehydrogenates 3HBA

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BDH2 dehydrogenates 3HBA Show undefined attributes

catalystActivity	[CatalystActivity:10620179] 3-hydroxybutyrate dehydrogenase activity of BDH2 tetramer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10620181
displayName	BDH2 dehydrogenates 3HBA
eventOf	[Pathway:R-DRE-77111] Synthesis of Ketone Bodies - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA - Danio rerio
inferredFrom	[Reaction:R-HSA-5696457] BDH2 dehydrogenates 3HBA - Homo sapiens
input	[SimpleEntity:R-ALL-5696461] 3HBA [cytosol] [SimpleEntity:R-ALL-29360] NAD+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	BDH2 dehydrogenates 3HBA
output	[SimpleEntity:R-ALL-29666] ACA [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73473] NADH [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5696457
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-77111] Synthesis of Ketone Bodies
(precedingEvent)	[Reaction:R-DRE-5694494] AACS ligates CoA-SH to ACA, forming ACA-CoA
(inferredTo)	[Reaction:R-HSA-5696457] BDH2 dehydrogenates 3HBA

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