Reactome | GSSG [mitochondrial matrix]

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GSSG [mitochondrial matrix] Show undefined attributes

compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[Reaction:R-SCE-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Saccharomyces cerevisiae [Reaction:R-SPO-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Schizosaccharomyces pombe [Reaction:R-DDI-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Dictyostelium discoideum [Reaction:R-CEL-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Caenorhabditis elegans [Reaction:R-GGA-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Gallus gallus [Reaction:R-XTR-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Xenopus tropicalis [Reaction:R-DRE-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Danio rerio [Reaction:R-SSC-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Sus scrofa [Reaction:R-BTA-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Bos taurus [Reaction:R-CFA-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Canis familiaris [Reaction:R-RNO-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Rattus norvegicus [Reaction:R-MMU-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Mus musculus [Reaction:R-HSA-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ - Homo sapiens
created	[InstanceEdit:1655880] Jassal, B, 2011-10-13
crossReference	[DatabaseIdentifier:29597] COMPOUND:C00127
dbId	1655882
displayName	GSSG [mitochondrial matrix]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9760900] D'Eustachio, Peter, 2022-01-05
name	GSSG oxidized glutathione glutathione disulfide
producedByEvent	[Reaction:R-CEL-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O - Caenorhabditis elegans [Reaction:R-GGA-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O - Gallus gallus [Reaction:R-XTR-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O - Xenopus tropicalis [Reaction:R-SSC-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O - Sus scrofa [Reaction:R-BTA-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O - Bos taurus [Reaction:R-CFA-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O - Canis familiaris [Reaction:R-RNO-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O - Rattus norvegicus [Reaction:R-MMU-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O - Mus musculus [Reaction:R-HSA-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O - Homo sapiens
referenceEntity	[ReferenceMolecule:chebi:58297] glutathione disulfide(2-) [ChEBI:58297]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-1655882
updateTrackers	[UpdateTracker:9903449] Update Tracker - [SimpleEntity:1655882] GSSG [mitochondrial matrix] - v80:[add_removeReferenceEntity]

Referrals

(updatedInstance)	[UpdateTracker:9903449] Update Tracker - [SimpleEntity:1655882] GSSG [mitochondrial matrix] - v80:[add_removeReferenceEntity]
(input)	[Reaction:R-SCE-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-SPO-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-DDI-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-CEL-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-GGA-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-XTR-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-DRE-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-SSC-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-BTA-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-CFA-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-RNO-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-MMU-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Reaction:R-HSA-3323079] GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+
(output)	[Reaction:R-CEL-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O [Reaction:R-GGA-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O [Reaction:R-XTR-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O [Reaction:R-SSC-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O [Reaction:R-BTA-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O [Reaction:R-CFA-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O [Reaction:R-RNO-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O [Reaction:R-MMU-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O [Reaction:R-HSA-3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O

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