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GSSG [mitochondrial matrix]
Stable Identifier
R-ALL-1655882
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
oxidized glutathione, glutathione disulfide
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
Detoxification of Reactive Oxygen Species (Bos taurus)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Bos taurus)
GSSG [mitochondrial matrix]
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Bos taurus)
GSSG [mitochondrial matrix]
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Sulfur amino acid metabolism (Bos taurus)
Degradation of cysteine and homocysteine (Bos taurus)
Sulfide oxidation to sulfate (Bos taurus)
Thiosulfate can transfer its sulfur atom to glutathione (Bos taurus)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to chemical stress (Caenorhabditis elegans)
Detoxification of Reactive Oxygen Species (Caenorhabditis elegans)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)
GSSG [mitochondrial matrix]
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Caenorhabditis elegans)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Detoxification of Reactive Oxygen Species (Canis familiaris)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
GSSG [mitochondrial matrix]
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Canis familiaris)
GSSG [mitochondrial matrix]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Sulfur amino acid metabolism (Canis familiaris)
Degradation of cysteine and homocysteine (Canis familiaris)
Sulfide oxidation to sulfate (Canis familiaris)
Thiosulfate can transfer its sulfur atom to glutathione (Canis familiaris)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
Detoxification of Reactive Oxygen Species (Danio rerio)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Danio rerio)
GSSG [mitochondrial matrix]
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Danio rerio)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to chemical stress (Dictyostelium discoideum)
Detoxification of Reactive Oxygen Species (Dictyostelium discoideum)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Dictyostelium discoideum)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
Detoxification of Reactive Oxygen Species (Gallus gallus)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Gallus gallus)
GSSG [mitochondrial matrix]
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Gallus gallus)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Detoxification of Reactive Oxygen Species (Homo sapiens)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
GSSG [mitochondrial matrix]
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Homo sapiens)
GSSG [mitochondrial matrix]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Sulfur amino acid metabolism (Homo sapiens)
Degradation of cysteine and homocysteine (Homo sapiens)
Sulfide oxidation to sulfate (Homo sapiens)
Thiosulfate can transfer its sulfur atom to glutathione (Homo sapiens)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
Detoxification of Reactive Oxygen Species (Mus musculus)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
GSSG [mitochondrial matrix]
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Mus musculus)
GSSG [mitochondrial matrix]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Sulfur amino acid metabolism (Mus musculus)
Degradation of cysteine and homocysteine (Mus musculus)
Sulfide oxidation to sulfate (Mus musculus)
Thiosulfate can transfer its sulfur atom to glutathione (Mus musculus)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Plasmodium falciparum)
Cellular responses to stress (Plasmodium falciparum)
Cellular response to chemical stress (Plasmodium falciparum)
Detoxification of Reactive Oxygen Species (Plasmodium falciparum)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Plasmodium falciparum)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
Detoxification of Reactive Oxygen Species (Rattus norvegicus)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
GSSG [mitochondrial matrix]
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Rattus norvegicus)
GSSG [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Sulfur amino acid metabolism (Rattus norvegicus)
Degradation of cysteine and homocysteine (Rattus norvegicus)
Sulfide oxidation to sulfate (Rattus norvegicus)
Thiosulfate can transfer its sulfur atom to glutathione (Rattus norvegicus)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Cellular response to chemical stress (Saccharomyces cerevisiae)
Detoxification of Reactive Oxygen Species (Saccharomyces cerevisiae)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Saccharomyces cerevisiae)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Cellular response to chemical stress (Schizosaccharomyces pombe)
Detoxification of Reactive Oxygen Species (Schizosaccharomyces pombe)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Schizosaccharomyces pombe)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
Detoxification of Reactive Oxygen Species (Sus scrofa)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
GSSG [mitochondrial matrix]
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Sus scrofa)
GSSG [mitochondrial matrix]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Sulfur amino acid metabolism (Sus scrofa)
Degradation of cysteine and homocysteine (Sus scrofa)
Sulfide oxidation to sulfate (Sus scrofa)
Thiosulfate can transfer its sulfur atom to glutathione (Sus scrofa)
GSSG [mitochondrial matrix]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
Detoxification of Reactive Oxygen Species (Xenopus tropicalis)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Xenopus tropicalis)
GSSG [mitochondrial matrix]
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Xenopus tropicalis)
GSSG [mitochondrial matrix]
External Reference Information
External Reference
glutathione disulfide(2-) [ChEBI:58297]
Participates
as an output of
Thiosulfate can transfer its sulfur atom to glutathione (Sus scrofa)
Thiosulfate can transfer its sulfur atom to glutathione (Bos taurus)
Thiosulfate can transfer its sulfur atom to glutathione (Canis familiaris)
Thiosulfate can transfer its sulfur atom to glutathione (Rattus norvegicus)
Thiosulfate can transfer its sulfur atom to glutathione (Mus musculus)
Thiosulfate can transfer its sulfur atom to glutathione (Homo sapiens)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Gallus gallus)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Xenopus tropicalis)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Danio rerio)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Bos taurus)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
as an input of
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Plasmodium falciparum)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Saccharomyces cerevisiae)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Schizosaccharomyces pombe)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Dictyostelium discoideum)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Caenorhabditis elegans)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Gallus gallus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Xenopus tropicalis)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Danio rerio)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Sus scrofa)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Bos taurus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Canis familiaris)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Rattus norvegicus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Mus musculus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Homo sapiens)
Other forms of this molecule
GSSG [extracellular region]
GSSG [cytosol]
Cross References
COMPOUND
C00127
ZINC
000003870129
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