Reactome | L-Orn [mitochondrial matrix]

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L-Orn [mitochondrial matrix] Show undefined attributes

compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[Reaction:R-PFA-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Plasmodium falciparum [Reaction:R-DDI-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Dictyostelium discoideum [Reaction:R-DRE-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Danio rerio [Reaction:R-HSA-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Homo sapiens [Reaction:R-CEL-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Caenorhabditis elegans [Reaction:R-DME-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Drosophila melanogaster [Reaction:R-MMU-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Mus musculus [Reaction:R-CFA-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Canis familiaris [Reaction:R-BTA-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Bos taurus [Reaction:R-SSC-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Sus scrofa [Reaction:R-XTR-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Xenopus tropicalis [Reaction:R-GGA-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Gallus gallus [Reaction:R-RNO-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Rattus norvegicus [Reaction:R-SPO-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Schizosaccharomyces pombe [Reaction:R-SCE-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Saccharomyces cerevisiae [Reaction:R-GGA-187588] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Gallus gallus [FailedReaction:R-HSA-9956527] OTC variants don't synthesize L-citrulline - Homo sapiens [Reaction:R-HSA-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Homo sapiens [Reaction:R-MMU-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Mus musculus [Reaction:R-RNO-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Rattus norvegicus [Reaction:R-CFA-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Canis familiaris [Reaction:R-BTA-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Bos taurus [Reaction:R-SSC-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Sus scrofa [Reaction:R-XTR-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Xenopus tropicalis [Reaction:R-GGA-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Gallus gallus [Reaction:R-DRE-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Danio rerio [Reaction:R-SPO-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Schizosaccharomyces pombe [Reaction:R-SCE-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Saccharomyces cerevisiae
created	[InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12
crossReference	[DatabaseIdentifier:29499] COMPOUND:C00077
dbId	113585
displayName	L-Orn [mitochondrial matrix]
inDisease	false
maxDepth	1
memberOf	[DefinedSet:R-ALL-8959775] SLC25A29 substrates [mitochondrial matrix]
modified	[InstanceEdit:9760757] D'Eustachio, Peter, 2022-01-03
name	L-Orn (S)-2,5-diaminovaleric acid L-ornithine (S)-2,5-Diaminopentanoic acid (S)-2,5-Diaminopentanoate
producedByEvent	[Reaction:R-GGA-187632] arginine + H2O => ornithine + urea - Gallus gallus [Reaction:R-PFA-452036] arginine + H2O => ornithine + urea [ARG2] - Plasmodium falciparum [Reaction:R-SCE-452036] arginine + H2O => ornithine + urea [ARG2] - Saccharomyces cerevisiae [Reaction:R-SPO-452036] arginine + H2O => ornithine + urea [ARG2] - Schizosaccharomyces pombe [Reaction:R-DDI-452036] arginine + H2O => ornithine + urea [ARG2] - Dictyostelium discoideum [Reaction:R-CEL-452036] arginine + H2O => ornithine + urea [ARG2] - Caenorhabditis elegans [Reaction:R-DME-452036] arginine + H2O => ornithine + urea [ARG2] - Drosophila melanogaster [Reaction:R-GGA-452036] arginine + H2O => ornithine + urea [ARG2] - Gallus gallus [Reaction:R-XTR-452036] arginine + H2O => ornithine + urea [ARG2] - Xenopus tropicalis [Reaction:R-DRE-452036] arginine + H2O => ornithine + urea [ARG2] - Danio rerio [Reaction:R-SSC-452036] arginine + H2O => ornithine + urea [ARG2] - Sus scrofa [Reaction:R-BTA-452036] arginine + H2O => ornithine + urea [ARG2] - Bos taurus [Reaction:R-CFA-452036] arginine + H2O => ornithine + urea [ARG2] - Canis familiaris [Reaction:R-MMU-452036] arginine + H2O => ornithine + urea [ARG2] - Mus musculus [Reaction:R-HSA-452036] arginine + H2O => ornithine + urea [ARG2] - Homo sapiens [Reaction:R-RNO-452036] arginine + H2O => ornithine + urea [ARG2] - Rattus norvegicus [Reaction:R-PFA-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Plasmodium falciparum [Reaction:R-DDI-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Dictyostelium discoideum [Reaction:R-CEL-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Caenorhabditis elegans [Reaction:R-DME-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Drosophila melanogaster [Reaction:R-HSA-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Homo sapiens [Reaction:R-MMU-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Mus musculus [Reaction:R-CFA-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Canis familiaris [Reaction:R-BTA-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Bos taurus [Reaction:R-SSC-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Sus scrofa [Reaction:R-XTR-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Xenopus tropicalis [Reaction:R-GGA-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Gallus gallus [Reaction:R-RNO-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Rattus norvegicus [Reaction:R-DRE-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Danio rerio [Reaction:R-SPO-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Schizosaccharomyces pombe [Reaction:R-SCE-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Saccharomyces cerevisiae [Reaction:R-GGA-187608] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Gallus gallus [Reaction:R-MMU-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Mus musculus [Reaction:R-HSA-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Homo sapiens [Reaction:R-RNO-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Rattus norvegicus [Reaction:R-CFA-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Canis familiaris [Reaction:R-BTA-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Bos taurus [Reaction:R-SSC-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Sus scrofa [Reaction:R-XTR-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Xenopus tropicalis [Reaction:R-GGA-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Gallus gallus [Reaction:R-DRE-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Danio rerio [Reaction:R-SPO-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Schizosaccharomyces pombe [Reaction:R-SCE-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Saccharomyces cerevisiae [Reaction:R-DME-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Drosophila melanogaster [Reaction:R-CEL-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Caenorhabditis elegans [Reaction:R-DDI-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) - Dictyostelium discoideum
referenceEntity	[ReferenceMolecule:chebi:46911] L-ornithinium(1+) [ChEBI:46911]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-113585
updateTrackers	[UpdateTracker:9890899] Update Tracker - [SimpleEntity:113585] L-Orn [mitochondrial matrix] - v52:[modifyName] [UpdateTracker:9903479] Update Tracker - [SimpleEntity:113585] L-Orn [mitochondrial matrix] - v80:[add_removeReferenceEntity] [UpdateTracker:9874292] Update Tracker - [SimpleEntity:113585] L-Orn [mitochondrial matrix] - v43:[addName]

Referrals

(input)	[Reaction:R-GGA-187588] carbamoyl phosphate + ornithine => citrulline + orthophosphate [FailedReaction:R-HSA-9956527] OTC variants don't synthesize L-citrulline [Reaction:R-PFA-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-DDI-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-DRE-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-HSA-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-CEL-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-DME-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-MMU-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-HSA-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Reaction:R-MMU-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Reaction:R-RNO-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Reaction:R-CFA-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Reaction:R-CFA-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-BTA-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Reaction:R-BTA-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-SSC-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Reaction:R-SSC-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-XTR-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Reaction:R-XTR-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-GGA-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Reaction:R-GGA-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-RNO-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-DRE-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Reaction:R-SPO-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Reaction:R-SPO-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] [Reaction:R-SCE-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Reaction:R-SCE-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]
(output)	[Reaction:R-GGA-187608] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-GGA-187632] arginine + H2O => ornithine + urea [Reaction:R-PFA-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-SCE-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-SPO-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-DDI-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-CEL-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-DME-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-GGA-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-XTR-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-DRE-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-SSC-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-BTA-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-CFA-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-MMU-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-HSA-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-RNO-452036] arginine + H2O => ornithine + urea [ARG2] [Reaction:R-PFA-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-DDI-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-CEL-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-DME-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-HSA-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-MMU-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-HSA-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-MMU-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-RNO-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-CFA-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-CFA-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-BTA-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-BTA-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-SSC-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-SSC-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-XTR-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-XTR-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-GGA-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-GGA-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-RNO-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-DRE-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-DRE-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-SPO-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-SPO-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-SCE-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] [Reaction:R-SCE-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-DME-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-CEL-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) [Reaction:R-DDI-70634] ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)
(hasMember)	[DefinedSet:R-ALL-8959775] SLC25A29 substrates [mitochondrial matrix]
(updatedInstance)	[UpdateTracker:9890899] Update Tracker - [SimpleEntity:113585] L-Orn [mitochondrial matrix] - v52:[modifyName] [UpdateTracker:9903479] Update Tracker - [SimpleEntity:113585] L-Orn [mitochondrial matrix] - v80:[add_removeReferenceEntity] [UpdateTracker:9874292] Update Tracker - [SimpleEntity:113585] L-Orn [mitochondrial matrix] - v43:[addName]

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