Reactome | Positive gene expression regulation by 'SREBP1A,1C:SCD gene [nucleoplasm]' SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Schema > RegulationReference > Entries

created	[InstanceEdit:9641190] Wu, G, 2019-04-04
dbId	9642623
displayName	Positive gene expression regulation by 'SREBP1A,1C:SCD gene [nucleoplasm]' SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
literatureReference	[LiteratureReference:1655613] SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver [LiteratureReference:1655604] Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2 [LiteratureReference:1655584] Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a [LiteratureReference:1655609] Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins [LiteratureReference:1655678] Cloning and characterization of the human stearoyl-CoA desaturase gene promoter: transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol [LiteratureReference:1655615] Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-1655858] Positive gene expression regulation by 'SREBP1A,1C:SCD gene [nucleoplasm]'
schemaClass	RegulationReference

(regulationReference)

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