Reactome | Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins

Schema > LiteratureReference > Entries

Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins Show undefined attributes

author	[Person:1655687] Pai, JT [Person:1655535] Guryev, O [Person:191325] Brown, MS [Person:191314] Goldstein, JL
created	[InstanceEdit:1655630] May, B, 2011-10-13
dbId	1655609
displayName	Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins
journal	J Biol Chem
pages	26138-48
pubMedIdentifier	9748295
schemaClass	LiteratureReference
title	Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins
url	http://www.ncbi.nlm.nih.gov/pubmed/9748295
volume	273
year	1998

Referrals

(literatureReference)

[Pathway:R-HSA-2426168] Activation of gene expression by SREBF (SREBP)
[RegulationReference:9642530] Positive gene expression regulation by 'SREBP1A,2:NF-Y:SP1:CYP51A1 gene [nucleoplasm]' Sterol regulatory element-binding proteins induce an entire pathway of cholesterol synthesis
[RegulationReference:9642623] Positive gene expression regulation by 'SREBP1A,1C:SCD gene [nucleoplasm]' SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
[Reaction:R-HSA-2426163] SREBP1A,2 binds the CYP51A1 promoter
[Reaction:R-HSA-2426154] SREBP1A,2 binds the LSS promoter
[RegulationReference:9641429] Positive gene expression regulation by 'SREBP1A,2:LSS gene [nucleoplasm]' Sterol regulatory element-binding proteins induce an entire pathway of cholesterol synthesis
[Reaction:R-HSA-2426162] SREBP1A,2 binds the HMGCR promoter
[RegulationReference:9642419] Positive gene expression regulation by 'SREBP1A,1C,2:NF-Y:FDPS gene [nucleoplasm]' Sterol regulatory element-binding proteins induce an entire pathway of cholesterol synthesis
[Reaction:R-HSA-2426146] SREBP1A,1C,2 binds the FDFT1 promoter
[Reaction:R-HSA-2426147] SREBP1A,1C,2 binds the FDPS promoter
[Reaction:R-HSA-2426150] SREBP1A,1C,2 binds the HMGCS1 promoter
[Reaction:R-HSA-2426148] SREBP1A,1C binds the FASN promoter
[BlackBoxEvent:R-HSA-9621410] HMGCR gene expression
[Reaction:R-HSA-9621411] EGR2 and SREBF2(1-484) dimer bind HMGCR gene

(author)

© 2026 Reactome

Cite Us!