Reactome | gain_of_function of Ligand-responsive p-6Y-EGFR mutants:p-Y472,771,783,1254-PLCG1 [plasma membrane]

Schema > EntityFunctionalStatus > Entries

created	[InstanceEdit:5637723] Orlic-Milacic, Marija, 2014-11-12
dbId	5637719
diseaseEntity	[Complex:R-HSA-1247846] Ligand-responsive p-6Y-EGFR mutants:p-Y472,771,783,1254-PLCG1 [plasma membrane]
displayName	gain_of_function of Ligand-responsive p-6Y-EGFR mutants:p-Y472,771,783,1254-PLCG1 [plasma membrane]
functionalStatus	[FunctionalStatus:2632527] gain_of_function via inframe_deletion [FunctionalStatus:5637717] gain_of_function via inframe_insertion [FunctionalStatus:2362351] gain_of_function via non_conservative_missense_variant
modified	[InstanceEdit:9631717] Wu, G, 2018-12-12
normalEntity	[Complex:R-HSA-212703] EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane]
schemaClass	EntityFunctionalStatus

(entityFunctionalStatus)

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